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Categories: Biology: Biochemistry, Biology: Cell Biology

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Abrupt shifts within complex systems such as the Earth's climate system are extremely hard to predict. Researchers have now succeeded in developing a new method to anticipate such tipping points in advance. They successfully tested the reliability of their method using one of the most severe abrupt climate changes of the past: the shift of the once-green Sahara into a desert.

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New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.

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Researchers hope their DIY machine will help designers around the world experiment with making their own, sustainable fashion and other textiles from a range of natural ingredients -- maybe even the chitin in crab shells or agar-agar from algae.

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Using genome reconstruction, scientists unveiled a once 'invisible' fish parasite present in many marine fish world-wide that belongs to the apicomplexans, one of the most important groups of parasites at a clinical level. However, it had gone unnoticed in previous studies. The parasite is geographically and taxonomically widespread in fish species around the planet, with implications for commercial fishing and oceanic food webs.

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A decade-long study has discovered huge genetic potential that is untapped in modern wheat varieties.

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Researchers have discovered new insights into the human heart's structure, revealing its evolutionary history. This study enhances understanding of heart development and its implications for treating heart disease.

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Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.

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A new study has shown for the first time that when sandhoppers want to enter a period of deep sleep each winter they have the means through which to increase the magnesium levels in their bodies -- in some instances more than doubling them. Essentially acting as a natural narcotic, the magnesium puts the sandhopper into a torpid state and this enforced rest means that the creatures can stay hidden in burrows up to 30cm beneath the beach surface, to some extent buffered from wintry conditions.

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A low vitamin B6 level has negative effects on brain performance. A research team has now found a way to delay the degradation of the vitamin.

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In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.

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Scientists have unraveled the ancestral history of one of the most iconic birds of prey in the current Iberian fauna: the Bonelli's eagle (Aquila fasciata). The study combines evidence from several disciplines, including palaeontology, genetics and ecology, to answer questions about when and why the Bonelli's eagle, a species primarily found in tropical and subtropical areas, colonized the Mediterranean Basin.

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An international research team has uncovered a new insight into human evolution by comparing humans' hearts with those of other great apes.

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Scientists are rethinking the evolution of vocal learning in birds. New Zealand's smallest bird, the rifleman or titipounamu, may have a rudimentary version of the talent possessed by parrots, hummingbirds and songbirds.

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A team of researchers has shown for the first time that fasting can reprogram the metabolism of natural killer cells, helping them to survive in the harsh environment in and around tumors, while also improving their cancer-fighting ability.

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The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry. The authors of the study stress, however, that their findings reflect experimental conditions in a laboratory setting and are not identical to large-scale industrial pasteurization processes for raw milk.

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Climate change is making it more difficult to raise cattle -- growth and reproduction are affected by heat -- so it's critical to breed cattle better adapted to a hotter and longer summer. A new study shows it's possible to identify the genes within breeds of cattle that would lead to the sweatiest, heat-tolerant offspring.

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New research may help close the nutrition gap between infant formula and human breast milk. The study shows how plants can be programmed to produce a diverse array of beneficial sugars found in human breast milk. The findings could lead to healthier and more affordable formula for babies, or more nutritious non-dairy plant milk for adults.

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With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.

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An analysis of reviews of translational biomedical research reveals that just 5% of therapies tested in animals reach regulatory approval for human use. The umbrella review summarizes other systematic reviews and provides high level evidence that while the rate of translation to human studies is 50%, there is steep drop off before final approval.

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Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. Researchers have now successfully edited genes using the CRISPR technique in a highly resilient tardigrade species previously impossible to study with genome-editing tools. The successful delivery of CRISPR to an asexual tardigrade species directly produces gene-edited offspring. The design and editing of specific tardigrade genes allow researchers to investigate which are responsible for tardigrade resilience and how such resilience can work.