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Categories: Biology: Cell Biology, Environmental: Biodiversity
Published A ketogenic diet could improve the response to pancreatic cancer therapy
(via sciencedaily.com) Original source Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome
(via sciencedaily.com) Original source Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Researchers call for genetically diverse models to drive innovation in drug discovery
(via sciencedaily.com) Original source Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.
Published Ecologists put an insect group on century-old map of biodiversity
(via sciencedaily.com) Original source The distribution of species around the globe is not a random process but an outcome resulting from several evolutionary mechanisms as well as past and current environmental limitations. As a result, since the mid-19th century, biologists have identified several main regions, called biogeographic realms, that depict these large ensembles of species around the world. These biogeographic realms represent one of the most fundamental descriptions of biodiversity on Earth and are commonly used in various fields of biology.
Published Scientists condition crocodiles to avoid killer cane toads
(via sciencedaily.com) Original source Scientists have trialled a new way to protect freshwater crocodiles from deadly invasive cane toads spreading across northern Australia.
Published Common equine painkiller disrupts assisted reproduction technique efficiency in mares
(via sciencedaily.com) Original source Researchers have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells -- called 'oocytes' -- to become viable embryos, which is a crucial step in assisted reproduction in horses.
Published Exciting advance in stem cell therapy
(via sciencedaily.com) Original source A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.
Published Study reveals urban trees suffer more from heat waves and drought than their rural counterparts
(via sciencedaily.com) Original source A recent study details how trees in New York City and Boston are more negatively impacted by heat waves and drought than trees of the same species in nearby rural forests. The finding highlights the challenges urban trees face in the context of climate change and underscores the importance of tailored urban forestry management as a tool for protecting tree species and reducing urban heat islands.
Published Significant link found between heme iron, found in red meat and other animal products, and type 2 diabetes risk
(via sciencedaily.com) Original source Higher intake of heme iron, the type found in red meat and other animal products -- as opposed to non-heme iron, found mostly in plant-based foods -- was associated with a higher risk of developing type 2 diabetes (T2D) in a new study. While the link between heme iron and T2D has been reported previously, the study's findings more clearly establish and explain the link.
Published Pit-building venom mixers
(via sciencedaily.com) Original source Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges
(via sciencedaily.com) Original source A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Expansion of agricultural land threatens climate and biodiversity
(via sciencedaily.com) Original source Food, feed, fiber, and bioenergy: The demand for agricultural raw materials is rising. How can additional cultivation areas be reconciled with nature conservation? Researchers have developed a land-use model that provides answers.
Published Protecting surf breaks mitigates climate change, helps coastal communities
(via sciencedaily.com) Original source Safeguarding places to hang ten and shoot the curl is an opportunity to simultaneously mitigate climate change, fuel tourism and help surrounding ecosystems, research has shown.
Published Rewriting the evolutionary history of critical components of the nervous system
(via sciencedaily.com) Original source A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published Starvation and adhesion drive formation of keratinocyte patterns in skin
(via sciencedaily.com) Original source Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
(via sciencedaily.com) Original source Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published Forest restoration can boost people, nature and climate simultaneously
(via sciencedaily.com) Original source Forest restoration can benefit humans, boost biodiversity and help tackle climate change simultaneously, new research suggests.
Published Pre-surgical antibody treatment might prevent heart transplant rejection
(via sciencedaily.com) Original source Anti-rejection regimens currently in use are broad immunosuppressive agents that make patients susceptible to infections. By using specific antibodies, it may be possible to just block the inflammation that leads to rejection but leave anti-microbial immunity intact.
Published Low magnesium levels increase disease risk
(via sciencedaily.com) Original source A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.