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Categories: Biology: Cell Biology, Environmental: Water
Published Drug-like inhibitor shows promise in preventing flu



Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.
Published Hope for a cure for visceral leishmaniasis, an often fatal infectious disease



Leishmaniasis is a tropical disease affecting a growing number of people worldwide. Each year, between 700,000 and 1 million new cases are reported. Caused by a protozoan parasite of the genus Leishmania, which is transmitted to humans by the simple bite of a sand fly, leishmaniasis comprises three clinical forms, of which the visceral form is the most serious. If left untreated, visceral leishmaniasis, also known as black fever, is almost always fatal.
Published Food for thought: Study links key nutrients with slower brain aging



A new study suggests better nutrition might help prevent cognitive decline. Working with a group of 100 cognitively healthy participants aged 65 to 75, a research team combined neuroscience with nutritional science to identify a specific nutrient profile linked with better performance on cognitive tests. Nutrient biomarkers identified via blood tests revealed a combination of fatty acids, antioxidants and carotenoids, and two forms of Vitamin E and choline -- very similar to the Mediterranean diet -- in the systems of those who showed slower than expected brain aging in MRI scans and cognitive assessments.
Published Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans



Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.
Published Clarifying the cellular mechanisms underlying periodontitis with an improved animal model



Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.
Published Green infrastructure plans need to consider historical racial inequalities



Urban greening projects should consider historical development patterns and past discriminatory practices to avoid exacerbating the unequal distribution of environmental benefits, says an urban and regional planning professor.
Published Warming climate intensifies flash droughts worldwide



Sudden, severe dry spells known as flash droughts are rising in intensity around the world, with a notable exception in mountainous Central Asia, where flash drought extent is shrinking, according to new research. Heat and changes to precipitation patterns caused by a warming climate are driving these trends, the study found.
Published A rise in sea urchins and related damage to kelp forests impacts Oregon's gray whales and their food



A recent boom in the purple sea urchin population off the southern Oregon Coast appears to have had an indirect and negative impact on the gray whales that usually forage in the region, a new study shows.
Published Genes provide hope for the survival of Arabia's last big cat



The release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction. Despite revealing extremely low levels of genetic diversity in the wild leopard population in Oman, the research team discovered higher levels of genetic diversity in captive leopards across the region. This important genetic resource has the potential for a major role in successful recovery of the Arabian leopard.
Published 'Vigorous melting' at Antarctica's Thwaites 'Doomsday' Glacier



Glaciologists show evidence of warm ocean water intruding kilometers beneath grounded ice at Thwaites Glacier in West Antarctica. The findings suggest that existing climate models are underestimating the impact of ocean and ice interactions in future sea level rise projections.
Published Digging up good news for microbial studies



Findings indicate that soil stored under refrigerated or air-dried conditions can still retain the needed information for understanding microbial community composition and structure for many years.
Published Unraveling the drought dilemma: Can reservoirs be a carbon source?



A team delves into the spatiotemporal patterns of water volume and total organic carbon concentration of agricultural reservoirs.
Published Diverse headgear in hoofed mammals evolved from common ancestor



From the small ossicones on a giraffe to the gigantic antlers of a male moose -- which can grow as wide as a car -- the headgear of ruminant hooved mammals is extremely diverse, and new research suggests that despite the physical differences, fundamental aspects of these bony adaptations likely evolved from a common ancestor.
Published New mechanisms behind antibiotic resistance



Two newly discovered mechanisms in bacteria have been identified that can contribute to the development of antibiotic resistance. Changing the number of copies of resistance genes in bacteria increases antibiotic resistance, and can do so very quickly. These two mechanisms, along with a third known mechanism, can occur independently of each other, even within the same bacterial cell.
Published Cloudy waters causes African fish to develop bigger eyes



Variations in water quality can impact the development of the visual system of one species of African fish, suggests a new study.
Published Expanding on the fundamental principles of liquid movement



We are living in a world surrounded by liquid and flow, and understanding the principles that govern its movement is vital in our high-tech world. Through mathematical modeling and experimentation, researchers have expanded on Tanner's Law -- a law in fluid dynamics that describes how non-volatile liquids move across surfaces -- to cover a wider range of volatile liquids. These findings have the potential to play a role in various liquid-based industries such as electronics cooling.
Published Modern plant enzyme partners with surprisingly ancient protein



Scientists have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected. This new research explored the origin and evolution of the biochemical machinery that builds lignin, a structural component of plant cell walls with significant impacts on the clean energy industry.
Published Scientists develop new geochemical 'fingerprint' to trace contaminants in fertilizer



An international team of scientists has revealed high levels of toxic metals in global phosphate fertilizers using a isotopic variants of the element strontium as a tracer to uncover metals in soil, groundwater and possibly the food chain.
Published Chronic wasting disease unlikely to move from animals to people



A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids -- deer, elk and moose -- to people. The findings are consistent with decades of similar research in animal models.
Published Sweet taste receptor affects how glucose is handled metabolically by humans



The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption and assimilation, as part of this system. A team found that stimulation and inhibition of the sweet receptor helps regulate glucose metabolism in humans and may have implications for managing such metabolic disorders as diabetes.