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Categories: Biology: Cell Biology, Geoscience: Volcanoes
Published Sandalwood oil by-product prevents prostate cancer development in mice



Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.
Published Nutrients direct intestinal stem cell function and affect aging



The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal stem cells and aging. The finding may make a difference when seeking ways to maintain the functional capacity of the aging gut.
Published Understanding chronic wasting disease in deer



A new collaborative study analyzed fecal samples to shed light on how the fatal disease impacts the gut microbiome in deer, providing a promising tool for disease surveillance.
Published Researchers uncover genetic factors for severe Lassa fever



Researchers report the results of the first ever genome-wide association study (GWAS) of a biosafety level 4 (BSL-4) virus. The team found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever. The work could lay the foundation for better treatments for Lassa fever and other similar diseases. The scientists are already working on a similar genetics study of Ebola susceptibility.
Published Researchers discover new cell that remembers allergies



Researchers have made a groundbreaking discovery: a new cell that remembers allergies.
Published Replacing animal-based foods with alternative proteins would unlock land for carbon removal



Researchers report that replacing 50% of animal products with alternative proteins by 2050 could free up enough agricultural land to generate renewable energy equivalent in volume to today's coal-generated power while simultaneously removing substantial CO2 from the atmosphere.
Published New research uncovers biological drivers of heart disease risk



Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.
Published Nature is particularly beneficial for people on lower income



Data from a representative sample of the Austrian population suggests that the relationship between nature contact and well-being is consistently stronger for people on lower than higher incomes. However, this pattern was only found when people actively visited nature and not when they merely lived near greenspaces. Findings suggest the availability, accessibility and use of green and blue spaces can play an important role in reducing income-related health inequalities.
Published Inexpensive, carbon-neutral biofuels are finally possible



When it comes to making fuel from plants, the first step has always been the hardest -- breaking down the plant matter. A new study finds that introducing a simple, renewable chemical to the pretreatment step can finally make next-generation biofuel production both cost-effective and carbon neutral.
Published Gut microbiome changes during pregnancy may influence immune system response



A new study identifies numerous pathways by which the gut microbiome may change the immune system.
Published Bacteria in the mouth linked to pulmonary fibrosis survival



Bacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF), finds a new study.
Published New approach to tackling bacterial infections identified



Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.
Published Researchers discover key to molecular mystery of how plants respond to changing conditions



A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.
Published Mystery of novel clove-like off-flavor in orange juice solved



A research team has solved the mystery of a novel clove-like off-flavor in orange juice, the cause of which was previously unknown. The study proves for the first time that the undesirable flavor note is due to the odorant 5-vinylguaiacol. As the results of the study show, the substance is mainly produced during the pasteurization process when residues of a cleaning agent react with a natural orange juice component under the influence of heat.
Published Scientists develop new biocontainment method for industrial organisms



Researchers have developed a new biocontainment method for limiting the escape of genetically engineered organisms used in industrial processes.
Published Remarkable cellular architecture and phylogenetic position of the mysterious arm-swinging protist meteora sporadica



Researchers studied in detail the strange protist Meteora sporadica, which swings its two lateral arms back and forth. The results of the study indicated that M. sporadica has a complex cytoskeleton that is closely related to Hemimastigophora, a group of organisms considered to be one of the deepest branches of eukaryotes.
Published How plants obtain nitrogen by supplying iron to symbiotic bacteria



Researchers have discovered peptide factors that function in the shoot and root systems to transport iron into the root nodules colonized by nitrogen-fixing bacteria. Moreover, these peptide factors regulate nitrogen homeostasis by maintaining a balance between nitrogen and iron concentrations in plants without rhizobial symbiosis.
Published Flu virus variants resistant to new antiviral drug candidate lose pathogenicity



Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a new study.
Published Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development



Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.
Published How T cells combat tuberculosis



Scientists have uncovered important clues to how human T cells combat Mycobacterium tuberculosis, the bacterium that causes TB.