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Categories: Biology: Cell Biology, Geoscience: Earthquakes

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Scientists have summarized microbial food production strategies.

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A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

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The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

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Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV infection.

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Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

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Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.

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Using machine learning, researchers have tied low-magnitude microearthquakes to the permeability of subsurface rocks beneath the Earth, a discovery that could have implications for improving geothermal energy transfer.

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Parasites thought only to infect tropical coral reefs have been discovered in a large variety of creatures in cold marine ecosystems along the Northeast Pacific, according to new research.

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Researchers have created a method that extracts over 80 percent of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain.

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Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.

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Traces of DNA in the stomachs of predatory snails give a team og geobiologists new insights into the ecology of placozoans.

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Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.

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Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

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A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

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Researchers decode repair mechanism during transcription of genetic information.

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Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water. The development provides a platform for the industrial-scale, tunable production of a material that holds great potential for turning the plastic industry green.

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Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

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Several similar large, fossilized bone fragments have been discovered in various regions across Western and Central Europe since the 19th century. The animal group to which they belonged is still the subject of much debate to this day. A study could now settle this dispute once and for all: The microstructure of the fossils indicates that they come from the lower jaw of a gigantic ichthyosaur. These animals could reach 25 to 30 meters in length, a similar size to the modern blue whale.

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Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.

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A new diagnostic tool developed by researchers can test for SARS-CoV-2 and Zika virus with the same or better accuracy as high-precision PCR tests in a matter of hours.