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Categories: Biology: Cell Biology, Geoscience: Severe Weather
Published Industrial societies losing healthy gut microbes



Our eating habits in industrialized societies are far removed from those of ancient humans. This is impacting our intestinal flora, it seems, as newly discovered cellulose degrading bacteria are being lost from the human gut microbiome, especially in industrial societies.
Published Genetic basis for the evolution of hair discovered in the clawed frog



The development of hair was of central importance for the evolution of mammals and thus also of humans. However, the evolutionary origin of the genetic program of hair was previously unknown. Researchers have now been able to show that important hair components and their genetic control have already evolved in amphibians. Human hair therefore shows unexpected similarities to the claws of clawed frogs.
Published How cells are ahead of the curve



The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Self-heating concrete is one step closer to putting snow shovels and salt out of business



Researchers recently reported on the science behind its special concrete, that can warm itself up when it snows, or as temperatures approach freezing.
Published Engineers measure pH in cell condensates



In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Fatty food before surgery may impair memory in old, young adults



Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults -- and, new research in animals suggests, even in young adults.
Published 'Noisy' roundworm brains give rise to individuality



Research has demonstrated individual differences in and successfully extracted commonalities from the whole-brain activity of roundworms. The researchers also found that computer simulations based on the whole-brain activity of roundworms more accurately reflect real-brain activity when they include so-called 'noise,' or probabilistic elements.
Published Meteorology: Weak polar vortex makes weather more predictable



Events in the stratosphere are making long-range weather in Northern Europe easier to forecast, researchers have discovered.
Published DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy



Researchers have created a DNA origami platform called DoriVac, whose core component is a self-assembling square block-shaped nanostructure. DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.
Published Machine learning classifier accelerates the development of cellular immunotherapies



Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published Protein fragments ID two new 'extremophile' microbes--and may help find alien life



Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.
Published Breakthrough could make automated dosing systems universal



Automated insulin dosing systems combine low-cost blood-glucose monitors with insulin pumps that use precision dosing to continuously regulate blood-sugar and hold it steady. Synthetic biologists have found a way to piggyback on the technology and make it universally applicable for the precision dosing of virtually any drug.
Published Diverse habitats help salmon weather unpredictable climate changes



Restored salmon habitat should resemble financial portfolios, offering fish diverse options for feeding and survival so that they can weather various conditions as the climate changes, a new study shows.
Published Small amounts of licorice raise blood pressure, study finds



It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.
Published Gut bacteria important for overcoming milk allergy



Researchers have discovered a link between gut bacteria and the success of milk-allergy oral immunotherapy. The study found that Bifidobacterium -- a genus of beneficial bacteria in the gut -- was associated with a higher chance of successful treatment. The finding may help in the development of more effective oral immunotherapies, perhaps by combining them with probiotic supplements.
Published It's hearty, it's meaty, it's mold



Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.
Published Alzheimer's drug fermented with help from AI and bacteria moves closer to reality



Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.
Published Tropical birds could tolerate warming better than expected, study suggests



We expect tropical animals to handle a certain degree of heat, but not wild swings in temperature. That seems to be true for tropical ectotherms, or 'cold-blooded' animals such as amphibians, reptiles, and insects. However, in a new study of 'warm-blooded' endotherms, a research team found tropical birds can handle thermal variation just fine.
Published New bioengineered protein design shows promise in fighting COVID-19



A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published Sleep-wake rhythm: Fish change our understanding of sleep regulation



Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.