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Categories: Biology: Cell Biology, Geoscience: Severe Weather
Published New discovery reveals how the egg controls sperm entry
(via sciencedaily.com) Original source After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Even cells know the importance of recycling
(via sciencedaily.com) Original source Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published New simpler and cost-effective forensics test helps identify touch DNA
(via sciencedaily.com) Original source Research has found a less expensive and easier to use test to learn more about forensic touch DNA. This research has important implications for forensic investigations and being able to identify DNA from a primary contact -- someone who may have committed the crime -- as well as secondary DNA that was inadvertently and indirectly transferred through touch.
Published Sulfur and the origin of life
(via sciencedaily.com) Original source A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published Tryptophan in diet, gut bacteria protect against E. coli infection
(via sciencedaily.com) Original source Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published Ready for the storm: Researchers analyze infrastructure, demographics to see where tornadoes are most disruptive
(via sciencedaily.com) Original source Researchers examined demographics, infrastructure and more than seven decades of weather data to determine which places in Kentucky are most vulnerable to tornadoes.
Published Study shows important role gut microbes play in airway health in persons with cystic fibrosis
(via sciencedaily.com) Original source Findings from a new study reflect the important role that the gut microbiome (communities of bacteria) plays in the airway health of persons with cystic fibrosis.
Published Drought, soil desiccation cracking, and carbon dioxide emissions: an overlooked feedback loop exacerbating climate change
(via sciencedaily.com) Original source Soil stores 80 percent of carbon on earth, yet with increasing cycles of drought, that crucial reservoir is cracking and breaking down, releasing even more greenhouse gases creating an amplified feedback loop that could accelerate climate change.
Published Steroid drugs used for HRT can combat E. coli and MRSA
(via sciencedaily.com) Original source Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published Simple trick could improve accuracy of plant genetics research
(via sciencedaily.com) Original source Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published Summer solstice triggers synchronized beech tree reproduction across Europe
(via sciencedaily.com) Original source A new study has found that the summer solstice acts as a 'starting gun' to synchronize beech tree reproduction across vast distances in Europe, affecting ecosystem functions.
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Scientists find weak points on Epstein-Barr virus
(via sciencedaily.com) Original source Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published History repeats as Coral Bay faces mass loss of coral and fish life
(via sciencedaily.com) Original source A perfect storm of environmental factors has seen a monumental loss of fish and coral life at a popular area of Ningaloo Reef in Western Australia's Gascoyne region -- however research into the event shows there is hope it will recover. In March 2022, during the annual coral spawning event, calm weather and limited tidal movement combined to trap the coral's eggs within Bills Bay, at the town of Coral Bay. This led to an excess of nutrients in the water which consumed more oxygen than usual -- causing massive numbers of fish and corals to die from asphyxiation.
Published How a natural compound from sea squirts combats cancer
(via sciencedaily.com) Original source Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published A coral superhighway in the Indian Ocean
(via sciencedaily.com) Original source Despite being scattered across more than a million square kilometers, new research has revealed that remote coral reefs across the Seychelles are closely related. Using genetic analyses and oceanographic modelling, researchers demonstrated for the first time that a network of ocean currents scatter significant numbers of larvae between these distant islands, acting as a 'coral superhighway.'
Published Gene flow in giraffes and what it means for their conservation
(via sciencedaily.com) Original source Giraffes, with their bizarre body plan, have always held a special place in the minds of evolutionary biologists and non-experts alike. In a new study whole-genome sequencing data was used to investigate the evolutionary processes occurring within giraffes. In particular, the authors were interested in establishing whether different populations of giraffes really have been isolated from each other for extended periods of time, which is normally a requirement before new species can arise.
Published India's water problems set to get worse as the world warms
(via sciencedaily.com) Original source Winter storms known as western disturbances that provide crucial snow and rainfall to northern India are arriving significantly later in the year.