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Categories: Biology: Cell Biology, Geoscience: Geography

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Warming temperatures are causing a steady rise in copper, zinc and sulfate in the waters of Colorado mountain streams affected by acid rock drainage. Concentrations of these metals have roughly doubled in these alpine streams over the past 30 years, presenting a concern for ecosystems, downstream water quality and mining remediation, according to a new study. Natural chemical weathering of bedrock is the source of the rising acidity and metals, but the ultimate driver of the trend is climate change, the report found, and the results point to lower stream volumes and exposure of rock once sealed away by ice as the likely causes.

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Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.

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A study of shallow-water fish communities on rocky reefs in south-eastern Australia has found climate change is helping tropical fish species invade temperate Australian waters.

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A new study has revealed breeding less-flatulent cows and restoring agricultural land could significantly reduce rising methane emission levels, which play a considerable role in climate change.

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Palaeontologists have solved a hundred-year-old mystery of how some fossil frogs preserve their fleshy parts -- it's all down to their skin. Palaeontologists studied 45-million-year-old fossil frogs from the Geiseltal site in central Germany. Remarkably, the fossils show full body outlines of the soft tissues. The team discovered that the excellent condition of the fossil frogs is due to preservation of ancient skin remnants.

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Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.

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Oases are important habitats and water sources for dryland regions, sustaining 10% of the world's population despite taking up about 1.5% of land area. But in many places, climate change and anthropogenic activities threaten oases' fragile existence. New research shows how the world's oases have grown and shrunk over the past 25 years as water availability patterns changed and desertification encroaches on these wet refuges.

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New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.

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Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.

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In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

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Letters written by the famous mountaineer George Mallory have been made available to a global audience for the first time, in the centenary year of his fatal attempt to scale Everest.

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Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.

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New research has uncovered a feedback loop that may be accelerating the melting of the floating portions of the West Antarctic Ice Sheet, pushing up global sea levels. The study sheds new light on the mechanisms driving the melting of ice shelves beneath the surface of the ocean, which have been unclear until now.

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An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.

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Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.

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Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.

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Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers have now found a completely novel use for Cnicin. Animal models as well as human cells have shown that Cnicin significantly accelerates axon (nerve fibers) growth.

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Tectonically active mountains play an important role in the natural CO2 regulation of the atmosphere. Competing processes take place here: At Earth's surface, erosion drives weathering processes that absorb or release CO2, depending on the type of rock. At depth, the heating and melting of carbonate rock leads to the outgassing of CO2 at the surface. In the central Italian Apennine Mountains, researchers have now investigated and balanced all of these processes in one region for the first time -- using, among others, analyses of the CO2 content in mountain rivers and springs.

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Dietary treatment is more effective than medications in irritable bowel syndrome (IBS). With dietary adjustments, more than seven out of ten patients had significantly reduced symptoms.

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Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.