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Categories: Biology: Cell Biology, Geoscience: Geochemistry
Published Fossil frogs share their skincare secrets
(via sciencedaily.com) Original source Palaeontologists have solved a hundred-year-old mystery of how some fossil frogs preserve their fleshy parts -- it's all down to their skin. Palaeontologists studied 45-million-year-old fossil frogs from the Geiseltal site in central Germany. Remarkably, the fossils show full body outlines of the soft tissues. The team discovered that the excellent condition of the fossil frogs is due to preservation of ancient skin remnants.
Published AI tool creates 'synthetic' images of cells for enhanced microscopy analysis
(via sciencedaily.com) Original source Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.
Published Liquid droplets shape how cells respond to change
(via sciencedaily.com) Original source New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
Published AI can improve Alzheimer's treatment through the 'gut-brain axis'
(via sciencedaily.com) Original source Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.
Published Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases
(via sciencedaily.com) Original source In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
Published Switching off the light to see better
(via sciencedaily.com) Original source Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.
Published Protein network dynamics during cell division
(via sciencedaily.com) Original source An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.
Published The enemy within: How pathogens spread unrecognized in the body
(via sciencedaily.com) Original source Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
Published Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent
(via sciencedaily.com) Original source Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.
Published New compound from blessed thistle promotes functional nerve regeneration
(via sciencedaily.com) Original source Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers have now found a completely novel use for Cnicin. Animal models as well as human cells have shown that Cnicin significantly accelerates axon (nerve fibers) growth.
Published 'Itinerant breeding' in East Coast shorebird species
(via sciencedaily.com) Original source A study has found direct evidence of a species -- the American woodcock, a migratory shorebird from eastern and central North America -- that overlaps periods of migration and reproduction, a rare breeding strategy known as 'itinerant breeding.'
Published The Italian central Apennines as a source of CO2
(via sciencedaily.com) Original source Tectonically active mountains play an important role in the natural CO2 regulation of the atmosphere. Competing processes take place here: At Earth's surface, erosion drives weathering processes that absorb or release CO2, depending on the type of rock. At depth, the heating and melting of carbonate rock leads to the outgassing of CO2 at the surface. In the central Italian Apennine Mountains, researchers have now investigated and balanced all of these processes in one region for the first time -- using, among others, analyses of the CO2 content in mountain rivers and springs.
Published Weather prediction models can also forecast satellite displacements
(via sciencedaily.com) Original source Researchers have found that modern weather models can accurately predict the energy that Earth emits and reflects into space, which directly affects the movements of low Earth-orbiting (LEO) satellites. By leveraging these models, the researchers gained insights into how LEO satellites respond to weather events below, such as tropical cyclones with tall and reflective clouds.
Published Toxic chemicals from microplastics can be absorbed through skin
(via sciencedaily.com) Original source Toxic chemicals used to flame-proof plastic materials can be absorbed into the body through skin, via contact with microplastics, new research shows.
Published Dietary treatment more effective than medicines in IBS
(via sciencedaily.com) Original source Dietary treatment is more effective than medications in irritable bowel syndrome (IBS). With dietary adjustments, more than seven out of ten patients had significantly reduced symptoms.
Published Key protein regulates immune response to viruses in mammal cells
(via sciencedaily.com) Original source Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Warming of Antarctic deep-sea waters contribute to sea level rise in North Atlantic, study finds
(via sciencedaily.com) Original source Analysis of mooring observations and hydrographic data suggest the Atlantic Meridional Overturning Circulation deep water limb in the North Atlantic has weakened. Two decades of continual observations provide a greater understanding of the Earth's climate regulating system.
Published Energy scientists unravel the mystery of gold's glow
(via sciencedaily.com) Original source EPFL researchers have developed the first comprehensive model of the quantum-mechanical effects behind photoluminescence in thin gold films; a discovery that could drive the development of solar fuels and batteries.
Published Light show in living cells
(via sciencedaily.com) Original source Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Why can zebrafish regenerate damaged heart tissue, while other fish species cannot?
(via sciencedaily.com) Original source A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.