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Categories: Biology: Cell Biology, Space: Exploration

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Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.

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Neuroscientists have discovered how the brain bidirectionally controls sensitivity to threats to initiate and complete escape behaviour in mice. These findings could help unlock new directions for discovering therapies for anxiety and post-traumatic stress disorder (PTSD).

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Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.

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A genetic 'off switch' that shuts down the process in which legume plants convert atmospheric nitrogen into nutrients has been identified for the first time by a team of international scientists.

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Dark energy -- a mysterious force pushing the universe apart at an ever-increasing rate -- was discovered 26 years ago, and ever since, scientists have been searching for a new and exotic particle causing the expansion. Physicists combined an optical lattice with an atom interferometer to hold atoms in place for up to 70 seconds -- a record for an atom interferometer -- allowing them to more precisely test for deviations from the accepted theory of gravity that could be caused by dark energy particles such as chameleons or symmetrons. Though they detected no anomalies, they're improving the experiment to perform more sensitive tests of gravity, including whether gravity is quantized.

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Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.

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Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.

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Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.

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Made famous in 1995 by NASA's Hubble Space Telescope, the Pillars of Creation in the heart of the Eagle Nebula have captured imaginations worldwide with their arresting, ethereal beauty. Now, NASA has released a new 3D visualization of these towering celestial structures using data from NASA's Hubble and James Webb space telescopes. This is the most comprehensive and detailed multiwavelength movie yet of these star-birthing clouds.

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The human body undergoes various transformations in space. However, a direct examination of organs and tissues is challenging. This study successfully identified these changes inside the body by analyzing tiny quantities of DNA and RNA molecules released from various tissues into the bloodstream while the astronauts were on the International Space Station (ISS).

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Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.

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Norcembranolide diterpenes, isolated from the soft corals of the genus Sinularia, are important compounds for the development of new drugs, owing to their diverse biological activities. However, total synthesis methods for these compounds are scarce. Now, a team of researchers has achieved the total synthesis of scabrolide F, a norcembranolide diterpene. They also revealed its non-toxic antifouling properties. This novel method can lead to the development of new drugs and antifouling agents.

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Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.

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Early analysis of the asteroid Bennu sample returned by NASA's OSIRIS-REx mission has revealed dust rich in carbon, nitrogen, and organic compounds, all of which are essential components for life as we know it. Dominated by clay minerals, particularly serpentine, the sample mirrors the type of rock found at mid-ocean ridges on Earth. The magnesium-sodium phosphate found in the sample hints that the asteroid could have splintered off from an ancient, small, primitive ocean world.

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The nine-banded armadillo, which ranges all the way from Argentina to Nebraska, is actually four separate species. One of the species, the Guianan long-nosed armadillo, is new to science. Meanwhile, the species that has migrated from Mexico to the United States (and is the official small mammal of Texas) is now called the Mexican long-nosed armadillo.

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New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.

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In October 2013 a researcher made a surprising discovery of Painted Lady Butterflies on the Atlantic beaches of French Guiana -- a species not typically found in South America. This unusual sighting prompted an international study to investigate the origin of these butterflies.

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The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.

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Solar physicists have revealed the interior structure of the sun's supergranules, a flow structure that transports heat from the sun's hidden interior to its surface. The researchers' analysis of the supergranules presents a challenge to the current understanding of solar convection.

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If aliens modified a planet in their solar system to make it warmer, we'd be able to tell. A new study identifies the artificial greenhouse gases that would be giveaways of a terraformed planet.