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Categories: Biology: Cell Biology, Geoscience: Oceanography
Published Researchers discover key gene for toxic alkaloid in barley
(via sciencedaily.com) Original source Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.
Published Cell division quality control 'stopwatch' uncovered
(via sciencedaily.com) Original source Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.
Published Eggs may not be bad for your heart after all
(via sciencedaily.com) Original source Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that over a four-month period cholesterol levels were similar among people who ate fortified eggs most days of the week compared with those who didn't eat eggs.
Published Connecting the dots to shape growth forces
(via sciencedaily.com) Original source Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published Synaptic protein change during development offers clues on evolution and disease
(via sciencedaily.com) Original source An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.
Published New method developed to isolate HIV particles
(via sciencedaily.com) Original source Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and hybrid material for targeted binding and separation of viral particles.
Published How extratropical ocean-atmosphere interactions can contribute to the variability of jet streams in the Northern Hemisphere
(via sciencedaily.com) Original source Ocean-atmosphere coupling, the exchange in energy between the ocean and atmosphere, influences teleconnection patterns, the climate effects across vast geographical areas. However, its impact outside the tropics is unclear. A group of researchers examined the effect of ocean coupling on atmospheric circulation patterns in the Northern Hemisphere. They found that extratropical ocean-atmosphere coupling enhances teleconnection patterns and causes more meandering westerly jet streams, which are linked to extreme weather events.
Published Artificial reef designed by MIT engineers could protect marine life, reduce storm damage
(via sciencedaily.com) Original source Engineers designed an 'architected' reef that can mimic the wave-buffering effects of natural reefs while providing pockets for marine life. The sustainable and cost-saving structure could dissipate more than 95 percent of incoming wave energy using a small fraction of the material normally needed.
Published A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
(via sciencedaily.com) Original source Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.
Published Scientists extract genetic secrets from 4,000-year-old teeth to illuminate the impact of changing human diets over the centuries
(via sciencedaily.com) Original source Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery
(via sciencedaily.com) Original source Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published New enzymatic cocktail can kill tuberculosis-causing mycobacteria
(via sciencedaily.com) Original source An enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
Published Milk on ice: Antarctic time capsule of whole milk powder sheds light on the enduring qualities--and evolution--of dairy products past and present
(via sciencedaily.com) Original source In a remarkable discovery, whole milk powder manufactured in New Zealand in 1907 and transported to Antarctica with explorers seeking the South Pole was unveiled after more than a century. The find has allowed dairy researchers to answer the question: Is the milk we enjoy today different from the milk consumed in previous generations? Now, a new comparative study has peered back in time to demonstrate that -- despite advancements in selective breeding and changes to farm practices -- milk of the past and milk today share more similarities than differences and are still crucial building blocks of human nutrition.
Published Old immune systems revitalized in mouse study, improving vaccine response
(via sciencedaily.com) Original source Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.
Published Evolution of the most powerful ocean current on Earth
(via sciencedaily.com) Original source The Antarctic Circumpolar Current plays an important part in global overturning circulation, the exchange of heat and CO2 between the ocean and atmosphere, and the stability of Antarctica's ice sheets. An international research team has now used sediments taken from the South Pacific to reconstruct the flow speed in the last 5.3 million years. Their data show that during glacial periods, the current slowed; during interglacials, it accelerated. Consequently, if the current global warming intensifies in the future, it could mean that the Southern Ocean stores less CO2 and that more heat reaches Antarctica.
Published Super permeable wearable electronics developed for stable, long-term biosignal monitoring
(via sciencedaily.com) Original source Super wearable electronics that are lightweight, stretchable and increase sweat permeability by 400-fold have been developed by scientists, enabling reliable long-term monitoring of biosignals for biomedical devices.
Published New testing approach improves detection of rare but emerging Powassan virus spread by deer ticks
(via sciencedaily.com) Original source Researchers have come up with a new, more accurate method for detecting in ticks the emerging Powassan virus, which can cause life-threatening neuroinvasive disease, including encephalitis and meningitis.
Published Researchers show that introduced tardigrade proteins can slow metabolism in human cells
(via sciencedaily.com) Original source Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.
Published Discovery of amino acid unveils how light makes plants open
(via sciencedaily.com) Original source Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.
Published Novel electrochemical sensor detects dangerous bacteria
(via sciencedaily.com) Original source Researchers have developed a novel sensor for the detection of bacteria. It is based on a chip with an innovative surface coating. This ensures that only very specific microorganisms adhere to the sensor -- such as certain pathogens. The larger the number of organisms, the stronger the electric signal generated by the chip. In this way, the sensor is able not only to detect dangerous bacteria with a high level of sensitivity but also to determine their concentration.