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Categories: Anthropology: Cultures, Biology: Cell Biology

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A white wine over 2,000 years old, of Andalusian origin, is the oldest wine ever discovered.

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Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.

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Cumulative culture -- the accumulation of technological modifications and improvements over generations -- allowed humans to adapt to a diversity of environments and challenges. But, it is unclear when cumulative culture first developed during hominin evolution. A new study concludes that humans began to rapidly accumulate technological knowledge through social learning around 600,000 years ago.

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The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice. While uncovering how the high fat, low carbohydrate diet boosts memory in older mice, scientists identified a new molecular signaling pathway that improves synapse function and helps explain the diet's benefit on brain health and aging.

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New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.

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Researchers hope their DIY machine will help designers around the world experiment with making their own, sustainable fashion and other textiles from a range of natural ingredients -- maybe even the chitin in crab shells or agar-agar from algae.

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Using genome reconstruction, scientists unveiled a once 'invisible' fish parasite present in many marine fish world-wide that belongs to the apicomplexans, one of the most important groups of parasites at a clinical level. However, it had gone unnoticed in previous studies. The parasite is geographically and taxonomically widespread in fish species around the planet, with implications for commercial fishing and oceanic food webs.

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Researchers have discovered new insights into the human heart's structure, revealing its evolutionary history. This study enhances understanding of heart development and its implications for treating heart disease.

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Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.

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A low vitamin B6 level has negative effects on brain performance. A research team has now found a way to delay the degradation of the vitamin.

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In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.

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An international research team has uncovered a new insight into human evolution by comparing humans' hearts with those of other great apes.

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Researchers share evidence that people's attitudes are deeply woven into language and culture across the globe and centuries.

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A team of researchers has shown for the first time that fasting can reprogram the metabolism of natural killer cells, helping them to survive in the harsh environment in and around tumors, while also improving their cancer-fighting ability.

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The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry. The authors of the study stress, however, that their findings reflect experimental conditions in a laboratory setting and are not identical to large-scale industrial pasteurization processes for raw milk.

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With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.

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An analysis of reviews of translational biomedical research reveals that just 5% of therapies tested in animals reach regulatory approval for human use. The umbrella review summarizes other systematic reviews and provides high level evidence that while the rate of translation to human studies is 50%, there is steep drop off before final approval.

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Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. Researchers have now successfully edited genes using the CRISPR technique in a highly resilient tardigrade species previously impossible to study with genome-editing tools. The successful delivery of CRISPR to an asexual tardigrade species directly produces gene-edited offspring. The design and editing of specific tardigrade genes allow researchers to investigate which are responsible for tardigrade resilience and how such resilience can work.

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Scientists have discovered a previously unknown link between two key pathways that regulate the immune system in mammals -- a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD). This family of disorders severely impacts the health and quality of life of more than 2 million people in the United States.

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Thousands of years ago, people in ancient Syria likely ate mostly grains, grapes, olives and a small amount of dairy and meat -- similar to today's 'Mediterranean diet,' according to a new study.