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Categories: Biology: Cell Biology, Chemistry: General
Published Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy
(via sciencedaily.com) Original source Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient. Now, researchers have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable traits, such as the ability to deliver cargo to a specific organ but not others or to work in multiple species. Other methods only look for capsids that have one trait at a time.
Published Bacteria encode hidden genes outside their genome--do we?
(via sciencedaily.com) Original source A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.
Published Researchers develop AI model that predicts the accuracy of protein--DNA binding
(via sciencedaily.com) Original source A new artificial intelligence model can predict how different proteins may bind to DNA.
Published Pioneering plasma-catalytic process for CO2 hydrogenation to methanol under ambient conditions
(via sciencedaily.com) Original source A research team reports a pioneering plasma-catalytic process for the hydrogenation of CO2 to methanol at room temperature and atmospheric pressure. This breakthrough addresses the limitations of traditional thermal catalysis, which often requires high temperatures and pressures, resulting in low CO2 conversion and methanol yield.
Published How do butterflies stick to branches during metamorphosis?
(via sciencedaily.com) Original source Most of us learned about butterfly metamorphosis as a kid -- a wriggly caterpillar molts its skin to form a tough chrysalis and emerges as a beautiful butterfly. But how exactly do chrysalises stay anchored as the butterfly brews within? Research shows that, despite their silks being weak and thin on their own, caterpillars can expertly spin them into chrysalis support structures resembling hook-and-loop fasteners and multi-strand safety tethers.
Published 3D laser printing with bioinks from microalgae
(via sciencedaily.com) Original source Microalgae such as the diatom Odontella aurita and the green alga Tetraselmis striata are especially suitable as 'biofactories' for the production of sustainable materials for 3D laser printing due to their high content in lipids and photoactive pigments. An international research team has succeeded for the first time in manufacturing inks for printing complex biocompatible 3D microstructures from the raw materials extracted from the microalgae.
Published Researchers make breakthrough in understanding species abundance
(via sciencedaily.com) Original source The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.
Published New technology uses light to engrave erasable 3D images
(via sciencedaily.com) Original source Researchers invented a technique that uses a specialized light projector and a photosensitive chemical additive to imprint two- and three-dimensional images inside any polymer. The light-based engraving remains in the polymer until heat or light are applied, which erases the image and makes it ready to use again. The technology is intended for any situation where having detailed, precise visual data in a compact and easily customizable format could be critical, such as planning surgeries and developing architectural designs.
Published Researchers crack a key celiac mystery
(via sciencedaily.com) Original source An interdisciplinary team of medical and engineering researchers has spent the last six years working to unlock a significant piece of the puzzle in the search for a cure: how and where the gluten response begins.
Published Finding pearls in the mud: Eco-friendly tungsten recovery from semiconductor waste
(via sciencedaily.com) Original source Semiconductor industry waste is typically seen as a costly disposal problem and an environmental hazard. But what if this waste could be transformed into a valuable resource? In an exciting development, researchers have unveiled an eco-friendly method to extract rare metals from semiconductor waste. This innovative approach not only recovers precious tungsten but also assesses its economic viability, offering a sustainable solution for waste management in the tech industry.
Published 3D bioprinting advances research on respiratory viruses
(via sciencedaily.com) Original source Researchers develop a microstructured 'artificial lung' model using bioprinting technology.
Published Effective new catalyst brings hope for cleaner energy, wastewater treatment, and green chemistry
(via sciencedaily.com) Original source A catalyst that significantly enhances ammonia conversion could improve wastewater treatment, green chemical and hydrogen production.
Published Microscopy technique 'paves way' for improving understanding of cellular functions
(via sciencedaily.com) Original source Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.
Published Chemists develop new sustainable reaction for creating unique molecular building blocks
(via sciencedaily.com) Original source Polymers can be thought of like trains: Just as a train is composed of multiple cars, polymers are made up of multiple monomers, and the couplings between the train cars are similar to the chemical bonds that link monomers together. While polymers have myriad applications -- from drug delivery to construction materials -- their structures and functions are restricted by the chemically similar monomer building blocks they're composed of. Now, chemists have developed a new reaction to create unique monomers in a controlled way. This reaction, which uses nickel as a catalyst, ultimately enables scientists to create polymers with unique and modifiable properties for drug delivery, energy storage, microelectronics and more.
Published Artificial compound eye to revolutionize robotic vision at lower cost but higher sensitivity
(via sciencedaily.com) Original source A research team has recently developed a novel artificial compound eye system that is not only more cost-effective, but demonstrates a sensitivity at least twice that of existing market products in small areas. The system promises to revolutionize robotic vision, enhance robots' abilities in navigation, perception and decision-making, while promoting commercial application and further development in human-robot collaboration.
Published Breakthrough in molecular control: New bioinspired double helix with switchable chirality
(via sciencedaily.com) Original source The control of artificial double-helical structures, which are essential for the development of high-order molecular systems, remains difficult. In a new study, researchers have developed novel double-helical monometallofoldamers that exhibit controllable helicity inversion and chiral information transfer, in response to external stimuli. These monometallofoldamers can lead to novel artificial supramolecular systems for molecular information transmission, amplification, replication, and other exciting applications in various fields of technology.
Published How ribosomes in our cells enable protein folding
(via sciencedaily.com) Original source Scientists discovered a role played by ribosomes during the folding of new proteins in cells.
Published Viral defense protein speeds up female stem cell production
(via sciencedaily.com) Original source A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.
Published Forever chemical pollution can now be tracked
(via sciencedaily.com) Original source Researchers developed a way to fingerprint organofluorine compounds -- sometimes called 'forever chemicals' --which could help authorities trace them to their source when they end up in aquifers, waterways or soil.
Published Do smells prime our gut to fight off infection?
(via sciencedaily.com) Original source In nematodes and humans, mitochondrial stress in the nervous system initiates a whole-body response that is most pronounced in the gut. A recent study showed that in nematodes, the odor of a pathogen triggers the nervous system to broadcast this response to the rest of the organism, prepping mitochondria in intestinal cells to fight a bacterial infection. Humans, too, may be able to sense pathogenic odors that prepare the gut for an infection.