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Categories: Biology: Cell Biology, Paleontology: Climate
Published Gut bacteria of malnourished children benefit from key elements in therapeutic food



New research has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children's underdeveloped gut microbiomes. The study also has identified the important bacterial strains that process these biochemical components. The findings may help guide treatment with a current food formulation and enable creation of new, more effective formulations in the future.
Published Enzymes can't tell artificial DNA from the real thing



Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Scientists unveil complete cell map of a whole mammalian brain



Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Nanoprobe with a barcode



Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.
Published Cells move in groups differently than they do when alone



A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published Mice possess natural gene therapy system



A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published Cell types in the eye have ancient evolutionary origins



In a comparative analysis across vertebrates of the many cell types in the retina -- mice alone have 130 types -- researchers concluded that most cell types have an ancient evolutionary history. Their remarkable conservation across species suggests that the retina of the last common ancestor of all mammals, which roamed the earth some 200 million year ago, must have had a complexity rivaling the retina of modern mammals.
Published A rare enzyme role change with bacterial defense system assembly



Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published A sugar analysis could reveal different types of cancer



In the future, a little saliva may be enough to detect an incipient cancer. Researchers have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.
Published Best areas for rewilding European bison



Simulations integrate historical records, fossils, and ancient DNA to reveal why the European bison nearly went extinct, and pinpoint optimal areas for conservation. Since the near-extinction of the European bison, enormous conservation efforts have helped to restore wild populations, and its numbers are on the rise. However, the study authors argue that ensuring the species's long-term protection and recovery requires understanding why they nearly went extinct in the first place. 'Our study also suggests areas where rewilding attempts are most likely to be successful,' said lead author July Pilowsky, currently a disease ecologist at Cary Institute of Ecosystem Studies. Pilowsky completed the research while working on their PhD at University of Adelaide and University of Copenhagen.
Published A new brew: Evaluating the flavor of roasted, lab-grown coffee cells



It may soon be time to wake up and smell the lab-grown coffee made from cultured plant cells. But it's not clear whether drinks from this product replicate coffee beans' complex flavors. Now, a study found that some of the comforting aromas and tastes of a conventional cup of coffee could be reproduced by roasting and brewing coffee cell cultures.
Published Underwater architects: The 'burrowing effect' of foraminifera on marine environments



Impact of single-cell organisms on sediment oxygen levels and bacterial diversity measured for the first time.
Published Extremely rare bird captured on film



A striking and extremely rare half-female, half-male bird has been spotted by a zoologist.
Published Clinical trial demonstrates that the ketogenic diet is effective at controlling polycystic kidney disease



It's official: The ketogenic diet proved to be effective at controlling polycystic kidney disease (PKD) in the first randomized controlled clinical trial of ketogenic metabolic therapy for PKD.
Published Zika's shape-shifting machinery, and a possible vulnerability



Viruses have limited genetic material -- and few proteins -- so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now researchers have shown how the virus does so much with so little and may have identified a therapeutic vulnerability.
Published How immune cells recognize their enemies



In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams a have identified new details in this process.
Published Breakthrough nanobody technology against liver inflammation



Researchers have developed a technique based on nanobody technology to prevent liver inflammation. Nanobodies, or single-domain antibodies, are fragments of antibodies that can selectively bind to a specific antigen. Because they are simple to produce and react in very specific ways, they are often used in various biotechnological, therapeutic and diagnostic applications.
Published New genes can arise from nothing



The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.
Published New insights into Zebra mussel attachment fibers offer potential solutions to combat invasive species, develop sustainable materials



A recent study has revealed that an unlikely event, occurring over 12 million years ago played an important role in shaping one of Canada's most damaging invasive species. Zebra and quagga mussels, belonging to the Dreissenid family, are widespread freshwater invasive species throughout North America that present a significant danger to native ecosystems by competing for resources. Using a fibrous anchor called a byssus, Dreissenid mussels contribute to biofouling on surfaces and obstruct intake structures in power stations and water treatment plants.
Published Molecular fossils shed light on ancient life



Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. New research combines geology and genetics, showing how changes in the early Earth prompted a shift in how animals eat.