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Biology: Biochemistry Biology: Cell Biology
Published

Research explores how a father's diet could shape the health of his offspring      (via sciencedaily.com)     Original source 

A mice study suggests a father's diet may shape the anxiety of his sons and the metabolic health of his daughters before they are even conceived.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers uncover human DNA repair by nuclear metamorphosis      (via sciencedaily.com)     Original source 

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Marine Biology: Zoology Chemistry: Biochemistry Ecology: Animals Ecology: Endangered Species Ecology: Invasive Species Ecology: Nature Ecology: Sea Life Environmental: General Geoscience: Oceanography
Published

New tagging method provides bioadhesive interface for marine sensors on diverse, soft, and fragile species      (via sciencedaily.com)     Original source 

Tagging marine animals with sensors to track their movements and ocean conditions can provide important environmental and behavioral information. Existing techniques to attach sensors currently largely rely on invasive physical anchors, suction cups, and rigid glues. While these techniques can be effective for tracking marine animals with hard exoskeletons and large animals such as sharks, individuals can incur physiological and metabolic stress during the tagging process, which can affect the quality of data collection. A newly developed soft hydrogel-based bioadhesive interface for marine sensors, referred to as BIMS, holds promise as an effective, rapid, robust, and non-invasive method to tag and track all sorts of marine species, including soft and fragile species. The BIMS tagging, which is also simple and versatile, can help researchers better understand animal behavior while also capturing oceanographic data critical for helping to better understand some impacts of climate change and for resource management.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

'One ring to rule them all': How actin filaments are assembled by formins      (via sciencedaily.com)     Original source 

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing filament. Furthermore, the scientists elucidated the reasons for the different speeds at which the different formins promote this process.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology
Published

How tardigrades can survive intense radiation      (via sciencedaily.com)     Original source 

Researchers have discovered that tardigrades -- microscopic animals famed for surviving harsh extremes -- have an unusual response to radiation.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Sea Life Geoscience: Geochemistry
Published

How blue-green algae manipulate microorganisms      (via sciencedaily.com)     Original source 

A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Unlocking the 'chain of worms'      (via sciencedaily.com)     Original source 

An international team of scientists has published a single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology
Published

Green-to-red transformation of Euglena gracilis using bonito stock and intense red light      (via sciencedaily.com)     Original source 

Euglena gracilis, often regarded as a 'superfood,' is a promising microalga with many health and nutritional benefits. In a recent study, researchers found an efficient and low-resource approach to trigger a reddening reaction in E. gracilis using red light and a bonito fish-based culture medium. This reaction is a sign of higher and diverse carotenoid content ratio, meaning the proposed method could help turn E. gracilis into an even more nutritious food source.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Geoscience: Geochemistry
Published

Researchers resolve old mystery of how phages disarm pathogenic bacteria      (via sciencedaily.com)     Original source 

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise. In response, scientists are elucidating the ways that bacteria-infecting viruses disarm these pathogens and ushering in the possibility of novel treatment methods.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology Biology: Zoology Ecology: Sea Life Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

Even the simplest marine organisms tend to be individualistic      (via sciencedaily.com)     Original source 

Sport junkie or couch potato? Always on time or often late? The animal kingdom, too, is home to a range of personalities, each with its own lifestyle. Biologists report on a surprising discovery: even simple marine polychaete worms shape their day-to-day lives on the basis of highly individual rhythms. This diversity is of interest not just for the future of species and populations in a changing environment, but also for medicine.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Starving cells hijack protein transport stations      (via sciencedaily.com)     Original source 

Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment      (via sciencedaily.com)     Original source 

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but researchers, studying nerve cells grown in the lab and mice, say that the proteasome's role may go well beyond that.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Animals Ecology: Sea Life Environmental: Ecosystems
Published

How seaweed became multicellular      (via sciencedaily.com)     Original source 

A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Molecular
Published

Decoding the language of cells: Unveiling the proteins behind cellular organelle communication      (via sciencedaily.com)     Original source 

A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Innovative antiviral defense with new CRISPR tool      (via sciencedaily.com)     Original source 

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics
Published

Researchers identify new genetic risk factors for persistent HPV infections      (via sciencedaily.com)     Original source 

Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV infection.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle      (via sciencedaily.com)     Original source 

Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
Published

New approach for combating 'resting' bacteria      (via sciencedaily.com)     Original source 

Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.