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Categories: Biology: Cell Biology, Paleontology: Climate
Published New trial highlights incremental progress towards a cure for HIV-1
(via sciencedaily.com) Original source A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them. The findings highlight how close -- yet still far -- researchers have come to developing a cure for HIV-1.
Published Interactions between flu subtypes predict epidemic severity more than virus evolution
(via sciencedaily.com) Original source Researchers have shed new light on how viral evolution, population immunity, and the co-circulation of other flu viruses shape seasonal flu epidemics.
Published Sandalwood oil by-product prevents prostate cancer development in mice
(via sciencedaily.com) Original source Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.
Published Nutrients direct intestinal stem cell function and affect aging
(via sciencedaily.com) Original source The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal stem cells and aging. The finding may make a difference when seeking ways to maintain the functional capacity of the aging gut.
Published Researchers studying ocean transform faults, describe a previously unknown part of the geological carbon cycle
(via sciencedaily.com) Original source This study reports widespread mineral carbonation of mantle rocks in an oceanic transform fueled by magmatic degassing of CO2. The findings describe a previously unknown part of the geological carbon cycle in transform faults that represent one of the three principal plate boundaries on Earth. The confluence of tectonically exhumed mantle rocks and CO2-rich alkaline basalt formed through limited extents of melting characteristic of the St. Paul's transform faults may be a pervasive feature at oceanic transform faults in general. Because transform faults have not been accounted for in previous estimates of global geological CO2 fluxes, the mass transfer of magmatic CO2 to the altered oceanic mantle and seawater may be larger than previously thought.
Published Understanding chronic wasting disease in deer
(via sciencedaily.com) Original source A new collaborative study analyzed fecal samples to shed light on how the fatal disease impacts the gut microbiome in deer, providing a promising tool for disease surveillance.
Published Researchers uncover genetic factors for severe Lassa fever
(via sciencedaily.com) Original source Researchers report the results of the first ever genome-wide association study (GWAS) of a biosafety level 4 (BSL-4) virus. The team found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever. The work could lay the foundation for better treatments for Lassa fever and other similar diseases. The scientists are already working on a similar genetics study of Ebola susceptibility.
Published Ancient pollen trapped in Greenland ice uncovers changes in Canadian forests over 800 years
(via sciencedaily.com) Original source The Greenland ice sheet lies thousands of miles from North America yet holds clues to the distant continent's environmental history. Nearly two miles thick in places, the ice sheet grows as snow drifts from the sky and builds up over time. But snow isn't the only thing carried in by air currents that swirl around the atmosphere, with microscopic pollen grains and pieces of ash mixing with snowfall and preserving records of the past in the ice. A new study examined these pollen grains and identified how eastern Canada's forests grew, retreated, and changed through time.
Published Ice cores provide first documentation of rapid Antarctic ice loss in the past
(via sciencedaily.com) Original source Researchers have uncovered the first direct evidence that the West Antarctic Ice Sheet shrunk suddenly and dramatically at the end of the Last Ice Age, around eight thousand years ago. The evidence, contained within an ice core, shows that in one location the ice sheet thinned by 450 meters -- that's more than the height of the Empire State Building -- in just under 200 years.
Published Researchers discover new cell that remembers allergies
(via sciencedaily.com) Original source Researchers have made a groundbreaking discovery: a new cell that remembers allergies.
Published What turned Earth into a giant snowball 700 million years ago? Scientists now have an answer
(via sciencedaily.com) Original source Inspired during field work in South Australia's Flinders Ranges, geoscientists have proposed that all-time low volcanic carbon dioxide emissions triggered a 57-million-year-long global 'Sturtian' ice age.
Published Replacing animal-based foods with alternative proteins would unlock land for carbon removal
(via sciencedaily.com) Original source Researchers report that replacing 50% of animal products with alternative proteins by 2050 could free up enough agricultural land to generate renewable energy equivalent in volume to today's coal-generated power while simultaneously removing substantial CO2 from the atmosphere.
Published New research uncovers biological drivers of heart disease risk
(via sciencedaily.com) Original source Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.
Published Nature is particularly beneficial for people on lower income
(via sciencedaily.com) Original source Data from a representative sample of the Austrian population suggests that the relationship between nature contact and well-being is consistently stronger for people on lower than higher incomes. However, this pattern was only found when people actively visited nature and not when they merely lived near greenspaces. Findings suggest the availability, accessibility and use of green and blue spaces can play an important role in reducing income-related health inequalities.
Published Inexpensive, carbon-neutral biofuels are finally possible
(via sciencedaily.com) Original source When it comes to making fuel from plants, the first step has always been the hardest -- breaking down the plant matter. A new study finds that introducing a simple, renewable chemical to the pretreatment step can finally make next-generation biofuel production both cost-effective and carbon neutral.
Published Gut microbiome changes during pregnancy may influence immune system response
(via sciencedaily.com) Original source A new study identifies numerous pathways by which the gut microbiome may change the immune system.
Published Bacteria in the mouth linked to pulmonary fibrosis survival
(via sciencedaily.com) Original source Bacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF), finds a new study.
Published New approach to tackling bacterial infections identified
(via sciencedaily.com) Original source Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.
Published Researchers discover key to molecular mystery of how plants respond to changing conditions
(via sciencedaily.com) Original source A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.
Published Mystery of novel clove-like off-flavor in orange juice solved
(via sciencedaily.com) Original source A research team has solved the mystery of a novel clove-like off-flavor in orange juice, the cause of which was previously unknown. The study proves for the first time that the undesirable flavor note is due to the odorant 5-vinylguaiacol. As the results of the study show, the substance is mainly produced during the pasteurization process when residues of a cleaning agent react with a natural orange juice component under the influence of heat.