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Categories: Biology: Cell Biology, Offbeat: Computers and Math
Published Unlocking the mystery of preexisting drug resistance: New study sheds light on cancer evolution
(via sciencedaily.com) Original source The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence of treatment due to a reduced growth rate, preexisting resistance is pervasive across diseases that evolve -- like cancer and pathogens -- defying conventional wisdom.
Published A new neural network makes decisions like a human would
(via sciencedaily.com) Original source Researchers are training neural networks to make decisions more like humans would. This science of human decision-making is only just being applied to machine learning, but developing a neural network even closer to the actual human brain may make it more reliable, according to the researchers.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer
(via sciencedaily.com) Original source Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Receptors make dairy cows a prime target for influenza
(via sciencedaily.com) Original source A study helps explain why dairy cows infected by highly pathogenic avian influenza are shedding the virus in their milk. Their findings could help develop biosecurity measures aimed at slowing the spread of the illness.
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle
(via sciencedaily.com) Original source A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.
Published How domestic rabbits become feral in the wild
(via sciencedaily.com) Original source After sequencing the genomes of nearly 300 rabbits from Europe, South America, and Oceania, researchers found that all of them had a mix of feral and domestic DNA. They say this was not what they had expected to find.
Published New ways to study spinal cord malformations in embryos
(via sciencedaily.com) Original source Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published A better way to make RNA drugs
(via sciencedaily.com) Original source RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Insight into one of life's earliest ancestors revealed in new study
(via sciencedaily.com) Original source Researchers have shed light on Earth's earliest ecosystem, showing that within a few hundred million years of planetary formation, life on Earth was already flourishing.
Published Neural networks made of light
(via sciencedaily.com) Original source Scientists propose a new way of implementing a neural network with an optical system which could make machine learning more sustainable in the future. In a new paper, the researchers have demonstrated a method much simpler than previous approaches.
Published A stealth fungus has decimated North American bats but scientists may be a step closer to treating white-nose syndrome
(via sciencedaily.com) Original source An invasive fungus that colonizes the skin of hibernating bats with deadly consequences is a stealthy invader that uses multiple strategies to slip into the small mammals' skin cells and quietly manipulate them to aid its own survival. The fungus, which causes the disease white-nose syndrome, has devastated several North American species over the last 18 years.
Published Muscle machine: How water controls the speed of muscle contraction
(via sciencedaily.com) Original source The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.
Published Nanoplastics and 'forever chemicals' disrupt molecular structures, functionality
(via sciencedaily.com) Original source Researchers have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS) -- commonly known as forever chemicals -- disrupt biomolecular structure and function. The work shows that the compounds can alter proteins found in human breast milk and infant formulas -- potentially causing developmental issues downstream.
Published Learning dance moves could help humanoid robots work better with humans
(via sciencedaily.com) Original source Engineers have trained a humanoid robot to perform a variety of expressive movements, from simple dance routines to gestures like waving, high-fiving and hugging, all while maintaining a steady gait on diverse terrains. This work marks a step towards building robots that perform more complex and human-like motions.
Published Mapping the world's fungi from air samples
(via sciencedaily.com) Original source Researchers have found that the key to a quick and cost-effective mapping of biodiversity has been right in front of our eyes all along, but at the same time invisible -- i.e., in the air that surrounds us.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed
(via sciencedaily.com) Original source International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin
(via sciencedaily.com) Original source An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published Researchers pinpoint brain cells that delay first bite of food
(via sciencedaily.com) Original source Do you grab a fork and take a first bite of cake, or say no and walk away? Our motivation to eat is driven by a complex web of cells in the brain that use signals from within the body, as well as sensory information about the food in front of us, to determine our behaviors. Now, scientists have identified a group of neurons in a small and understudied region of the brain -- the parasubthalamic nucleus (PSTN) -- that controls when an animal decides to take a first bite of food.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness
(via sciencedaily.com) Original source Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published A new twist on artificial 'muscles' for safer, softer robots
(via sciencedaily.com) Original source Engineers have developed a new soft, flexible device that makes robots move by expanding and contracting -- just like a human muscle. To demonstrate their new device, called an actuator, the researchers used it to create a cylindrical, worm-like soft robot and an artificial bicep. In experiments, the cylindrical soft robot navigated the tight, hairpin curves of a narrow pipe-like environment, and the bicep was able to lift a 500-gram weight 5,000 times in a row without failing.