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Categories: Biology: Cell Biology, Offbeat: Computers and Math
Published New, modified CRISPR protein can fit inside virus used for gene therapy
(via sciencedaily.com) Original source Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published Scientists invent 'living bioelectronics' that can sense and heal skin
(via sciencedaily.com) Original source Reaserchers have created a prototype for what they call 'living bioelectronics': a combination of living cells, gel, and electronics that can integrate with living tissue. Tests in mice found that the devices could continuously monitor and improve psoriasis-like symptoms, without irritating skin.
Published Researchers expose new symbiosis origin theories, identify experimental systems for plant life
(via sciencedaily.com) Original source Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.
Published Researchers apply quantum computing methods to protein structure prediction
(via sciencedaily.com) Original source Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction.
Published Blood flow makes waves across the surface of the mouse brain
(via sciencedaily.com) Original source Researchers have, for the first time, visualized the full network of blood vessels across the cortex of awake mice, finding that blood vessels rhythmically expand and contract leading to 'waves' washing across the surface of the brain. These findings improve the understanding of how the brain receives blood, though the function of the waves remains a mystery.
Published hnRNPM, a guardian of the integrity of cellular protein production
(via sciencedaily.com) Original source Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed
(via sciencedaily.com) Original source New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes
(via sciencedaily.com) Original source A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published Acute sense of touch helps hummingbirds hover near a flower without bumping into it
(via sciencedaily.com) Original source Hummingbird flight mechanics have been well studied but far less is known about how their sense of touch helps them sip nectar from a flower without bumping into it. Most of what scientists know about how touch is processed in the brain comes from studies on mammals, but bird brains are very different from mammal brains. New research shows that touch and air pressure on the wings and legs activate specific clusters of neurons in two regions of the forebrain to create a map of their body, which may help hummingbirds make nuanced adjustments to flight.
Published Complete X and Y chromosome sequences of living great ape species determined
(via sciencedaily.com) Original source Newly generated, complete genomes for the sex chromosomes of six primate species may inform conservation of these endangered species and shed light on sex-related genetic diseases in both humans and our closest living relatives.
Published New antibiotic kills pathogenic bacteria, spares healthy gut microbes
(via sciencedaily.com) Original source Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.
Published New research approach: Exploring the mouthfeel of food with a microscope
(via sciencedaily.com) Original source A new perspectives article focuses on different ways to study the mouthfeel of food using atomic force microscopy to better understand the biophysical mechanisms that contribute to taste sensations in a broader sense. New findings in this area could drive the development of health-promoting products that contain less salt, fat, sugar and calories but still have a convincing mouthfeel.
Published Enhancing cybersecurity with 'moving trees'
(via sciencedaily.com) Original source Researchers propose a new tree-inspired one-time password scheme that provides security and privacy while supporting changing user environments.
Published Heart healthy behaviors may help reverse rapid cell aging
(via sciencedaily.com) Original source The benefits gained with higher lifestyle scores may be associated with the positive influence of heart disease risk factors on the aging of the body and its cells, finds a new study in the Journal of the American Heart Association
Published Public have no difficulty getting to grips with an extra thumb, study finds
(via sciencedaily.com) Original source Researchers have shown that members of the public have little trouble in learning very quickly how to use a third thumb -- a controllable, prosthetic extra thumb -- to pick up and manipulate objects. The team tested the robotic device on a diverse range of participants, which they say is essential for ensuring new technologies are inclusive and can work for everyone.
Published Bird flu: Diverse range of vaccines platforms 'crucial' for enhancing human pandemic preparedness
(via sciencedaily.com) Original source Review of research to-date suggests vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains.
Published Intermittent fasting shows promise in improving gut health, weight management
(via sciencedaily.com) Original source Participants following an intermittent fasting and protein-pacing regimen, which involves evenly spaced protein intake throughout the day, saw better gut health, weight loss and metabolic responses. These benefits were notably greater than those seen with simple calorie restriction. The findings could advance our understanding of the relationship between the gut microbiome and metabolism and improve strategies for managing obesity.
Published Scientists identify gene that could lead to resilient 'pixie' corn
(via sciencedaily.com) Original source A widely found gene in plants has been newly identified as a key transporter of a hormone that influences the size of corn. The discovery offers plant breeders a new tool to develop desirable dwarf varieties that could enhance the crop's resilience and profitability.
Published When should you neuter or spay your dog?
(via sciencedaily.com) Original source A new study updates guidelines for when you should neuter or spay your dog to prevent increased risk of cancer or joint disorders.
Published Bringing back an ancient bird
(via sciencedaily.com) Original source Using ancient DNA extracted from the toe bone of a museum specimen, biologists have sequenced the genome of an extinct, flightless bird called the little bush moa, shedding light into an unknown corner of avian genetic history. The work is the first complete genetic map of the turkey-sized bird whose distant living cousins include the ostrich, emu, and kiwi.