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Categories: Biology: Cell Biology, Offbeat: Paleontology and Archeology
Published Obesity linked to neurodegeneration through insulin resistance
(via sciencedaily.com) Original source Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published 'Biodiversity time machine' provides insights into a century of loss
(via sciencedaily.com) Original source AI analysis shows pollution levels, extreme weather events and increasing temperatures devastates biodiversity in freshwater lakes.
Published French love letters confiscated by Britain finally read after 265 years
(via sciencedaily.com) Original source Over 100 letters sent to French sailors by their fianc es, wives, parents and siblings -- but never delivered -- have been opened and studied for the first time since they were written in 1757-8.
Published 450-million-year-old organism finds new life in Softbotics
(via sciencedaily.com) Original source Researchers have used fossil evidence to engineer a soft robotic replica of pleurocystitids, a marine organism that existed nearly 450 million years ago and is believed to be one of the first echinoderms capable of movement using a muscular stem.
Published Long-distance weaponry identified at the 31,000-year-old archaeological site of Maisières-Canal
(via sciencedaily.com) Original source The hunter-gatherers who settled on the banks of the Haine, a river in southern Belgium, 31,000 years ago were already using spearthrowers to hunt their game. The material found at the archaeological site of Maisières-Canal permits establishing the use of this hunting technique 10,000 years earlier than the oldest currently known preserved spearthrowers. This discovery is prompting archaeologists to reconsider the age of this important technological innovation.
Published Plants' ingenious defense against mutational damage
(via sciencedaily.com) Original source How do plants deal with mutations in their 'power stations'? By exploiting randomness to create diversity, say researchers.
Published Some benefits of exercise stem from the immune system
(via sciencedaily.com) Original source Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.
Published Seeing the unseen: How butterflies can help scientists detect cancer
(via sciencedaily.com) Original source There are many creatures on our planet with more advanced senses than humans. Turtles can sense Earth's magnetic field. Mantis shrimp can detect polarized light. Elephants can hear much lower frequencies than humans can. Butterflies can perceive a broader range of colors, including ultraviolet (UV) light.
Published Viral impostors: Breakthrough for virus research
(via sciencedaily.com) Original source The penetration of viruses into cells can now be tracked with unprecedented accuracy thanks to an innovative design for pseudoviruses.
Published New secrets about cat evolution revealed
(via sciencedaily.com) Original source By comparing genomes of several cat species, the project has helped researchers understand why cat genomes tend to have fewer complex genetic variations (such as rearrangements of DNA segments) than other mammal groups, like primates. It also revealed new insights into which parts of cat DNA are most likely to evolve rapidly and how they play a role in species differentiation.
Published New antibiotic approach proves promising against lyme bacterium
(via sciencedaily.com) Original source Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence
(via sciencedaily.com) Original source Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.
Published Research outlines how sex differences have evolved
(via sciencedaily.com) Original source Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.
Published Female sex determining gene identified in mice
(via sciencedaily.com) Original source Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells
(via sciencedaily.com) Original source An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits
(via sciencedaily.com) Original source Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.
Published Observation of a virus attaching to another virus
(via sciencedaily.com) Original source 'Satellite' viruses must be in proximity to their 'helper' virus to replicate, but this research reports the first documented case of a satellite virus attaching itself to its helper virus. Out of 50 observed helpers, 40 had a satellite bound. Bioinformatic analysis of the satellite and helper viruses' genomes provides clues as to why the satellite may have evolved to attach to the helper, and suggests this pair may have been co-evolving for about 100 million years.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells
(via sciencedaily.com) Original source In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New antibodies neutralize resistant bacteria
(via sciencedaily.com) Original source Broadly neutralizing antibodies are already being used to fight viruses. This approach could also help to treat infections with multi-resistant bacteria in the future.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells
(via sciencedaily.com) Original source Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.