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Categories: Biology: Cell Biology, Offbeat: Paleontology and Archeology
Published New pipeline makes valuable organic acid from plants -- saving money and emissions
(via sciencedaily.com) Original source In a breakthrough for environmentally friendly chemical production, researchers have developed an economical way to make succinic acid, an important industrial chemical, from sugarcane. The team has created a cost-effective, end-to-end pipeline for this valuable organic acid by engineering a tough, acid-tolerant yeast as the fermenting agent, avoiding costly steps in downstream processing. Succinic acid is a widely used additive for food and beverages and has diverse applications in agricultural and pharmaceutical products. This same pipeline can be used to produce other industrially important organic acids from crops rather than petroleum-based processes, significantly reducing greenhouse gas emissions.
Published Gut bacteria found in wild wolves may be key to improving domestic dogs' health
(via sciencedaily.com) Original source Gut microbes found in wild wolves may be the key to alleviating a debilitating gastrointestinal condition common to domestic dogs.
Published When cells go boom: Study reveals inflammation-causing gene carried by millions
(via sciencedaily.com) Original source Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.
Published How new plant cell walls change their mechanical properties after cell division
(via sciencedaily.com) Original source Scientists reveal new plant cell walls can have significantly different mechanical properties compared to surrounding parental cell walls, enabling cells to change their local shape and influence the growth of plant organs.
Published DNA from discarded whale bones suggests loss of genetic diversity due to commercial whaling
(via sciencedaily.com) Original source Commercial whaling in the 20th century decimated populations of large whales but also appears to have had a lasting impact on the genetic diversity of today’s surviving whales, new research shows.
Published Preventing spread of parasitic DNA in our genomes
(via sciencedaily.com) Original source Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published Swap red meat for Quorn protein to improve heart health and reduce waist circumference, study finds
(via sciencedaily.com) Original source People looking to reduce their cholesterol and trim fat from around their waist could try swapping meat for Quorn protein, according to the findings from a new study, which saw positive effects in both areas in just two weeks.
Published Water makes all the difference
(via sciencedaily.com) Original source Water is a major driving force in the formation of separate reaction compartments within cells.
Published A hygiene program for chromosomes
(via sciencedaily.com) Original source Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.
Published Distributed workload in the fly brain
(via sciencedaily.com) Original source To distinguish motion patterns, a neuronal computation is performed three times in a row.
Published A more effective experimental design for engineering a cell into a new state
(via sciencedaily.com) Original source A new machine-learning approach helps scientists more efficiently identify the optimal intervention to achieve a certain outcome in a complex system, such as genome regulation, requiring far fewer experimental trials than other methods.
Published Researchers studied thousands of fertility attempts hoping to improve IVF
(via sciencedaily.com) Original source By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.
Published Edges cause cilia to quickly synchronize their beating pattern
(via sciencedaily.com) Original source Border regions can cause cilia to coordinate their motion creating a unidirectional wave that is essential for biological functions. Scientists proposed a new model describing this synchronized pattern driven by the border region.
Published Small but mighty new gene editor
(via sciencedaily.com) Original source A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but at one-third the size of the Cas9 enzyme commonly used for gene editing. The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.
Published Allergy study on 'wild' mice challenges the hygiene hypothesis
(via sciencedaily.com) Original source The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis. Now, an article challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice.
Published Solving a sticky, life-threatening problem
(via sciencedaily.com) Original source Researchers have zeroed in on C. auris' uncanny ability to stick to everything from skin to catheters and made a startling discovery: it uses a protein similar to that used by barnacles and mollusks.
Published Did animal evolution begin with a predatory lifestyle?
(via sciencedaily.com) Original source Surprising findings on the development of sea anemones suggest that a predatory lifestyle molded their evolution and had a significant impact on the origin of their nervous system. The researchers were able to show that the young life stages (larvae) of the small sea anemone Aiptasia actively feed on living prey and are not dependent on algae. To capture its prey, the anemone larvae use specialized stinging cells and a simple neuronal network.
Published A lethal parasite's secret weapon: Infecting non-immune cells
(via sciencedaily.com) Original source The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.
Published Polyps as pixels: Innovative technique maps biochemistry of coral reefs
(via sciencedaily.com) Original source Using an innovative new approach to sampling corals, researchers are now able to create maps of coral biochemistry that reveal with unprecedented detail the distribution of compounds that are integral to the healthy functioning of reefs.
Published An advance in cryo-EM could be a significant boon for research on potential cancer therapies
(via sciencedaily.com) Original source A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.