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Categories: Biology: Cell Biology, Offbeat: Paleontology and Archeology

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Palaeontologists have discovered X-ray evidence of proteins in fossil feathers that sheds new light on feather evolution.

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Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.

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Engineers have devised a new solution to control a major agricultural menace, root-damaging nematodes. Using plant viruses, the researchers created nanoparticles that can deliver pesticide molecules to previously inaccessible depths in the soil. This 'precision farming' approach could potentially minimize environmental toxicity and cut costs for farmers.

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To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.

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In a new study in mice, researchers have uncovered a crucial component for restoring functional activity after spinal cord injury. The neuroscientists have shown that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.

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Living things from plants to humans must constantly adjust the chemical soup of proteins -- the workhorse molecules of life -- inside their cells to adapt to stress or changing conditions. Now, researchers have identified a previously unknown molecular mechanism that helps explain how they do it. A team now reveals hairpin-like structures of mRNA that, by zipping and unzipping, help cells change the mix of proteins they produce when under stress.

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An international study has documented post-mortem bone modifications not linked to consumption.

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How do our muscles respond at the molecular level to exercise? Researchers have unraveled the cellular basis and signaling pathways responsible for the positive impact of physical activity on our overall health. Regulatory T cells, a type of immune cell, play a critical role in ensuring proper muscle function. These novel insights are paving the path towards precision medicines targeting metabolic disorders like obesity and diabetes, as well as muscle-related illnesses.

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Half a million years ago, earlier than was previously thought possible, humans were building structures made of wood, according to new research.

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Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.

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A groundbreaking study is reshaping our understanding of crocodile evolution by pinpointing the onset of slow growth rates to the Late Triassic period, much earlier than the previously assumed Early Jurassic timeline. The research highlights newly discovered fossil crocodile ancestors (known as crocodylomorphs) that exhibited slow growth rates, similar to modern-day crocodilians. Intriguingly, these early crocodylomorphs were not the lethargic, semi-aquatic creatures we are familiar with today; they were small, active, and fully terrestrial. The study also suggests that this slow-growth strategy was not a mere evolutionary quirk but a survival mechanism, as only the slow-growing crocodylomorphs managed to survive the End-Triassic mass extinction. This stands in stark contrast to the fast-growing dinosaurs of the same era, setting the stage for the divergent evolutionary paths that would later define their modern descendants.

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A research team has uncovered a treasure trove of uncharacterized proteins. Embracing the recent deep learning revolution, they discovered hundreds of new protein families and even a novel predicted protein fold.

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Biologists have discovered why an enzyme is important for the survival of fruit flies, even though it can shorten their lives under certain conditions.

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Plants are often attributed with abilities similar to those known in the animal or human world. Trees are said to have feelings and can therefore care for their offspring, like mothers. Researchers analyzed the claims in two popular publications on forests and reached the conclusion that conjecture is equated with fact. They warn against 'anthropomorphizing' plants.

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Marine virologists analyzed sediment from the Mariana Trench, the deepest place on Earth, and identified a new bacteriophage.

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Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.

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Hearing the sound of a newborn's wail can trigger the release of oxytocin, a brain chemical that controls breast-milk release in mothers, a new study in rodents shows. Researchers found that once prompted, this flood of hormones continues for roughly five minutes before tapering off, enabling mothers to feed their young until they are sated or begin crying again.

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X-rays of an ancient jawless fish shows earliest-known example of internal cartilage skull, unlike that of any other known vertebrate.

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A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational changes, that help to explain the enzyme's biochemistry. This work might help researchers engineer enzymes that facilitate unusual chemistry or are highly efficient at room temperature that are useful in chemical industry.

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Using engineered microbes as microscopic factories has given the world steady sources of life-saving drugs, revolutionized the food industry, and allowed us to make sustainable versions of valuable chemicals previously made from petroleum. But behind each biomanufactured product on the market today is the investment of years of work and many millions of dollars in research and development funding. Scientists want to help the burgeoning industry reach new heights by accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.