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Categories: Biology: Cell Biology, Chemistry: Biochemistry

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Mosses, liverworts, ferns and algae may offer an exciting new research frontier in the global challenge of protecting crops from the threat of disease.

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A summer 2022 research cruise that detected a massive and highly toxic harmful algal bloom (HAB) in the Bering Strait has provided a dramatic example of science that utilized new technology to track a neurotoxic HAB and effectively communicate that information in real-time to protect remote communities in coastal Alaska.

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Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.

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By teasing apart the therapeutic benefits from the adverse effects of new generation obesity medications, researchers found a population of neurons in the brain that controls food intake without causing nausea in an animal model.

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An unexpected find has enabled important progress to be made in the battle against harmful bacteria.

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Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe's populations long before the major plague outbreaks of the Middle Ages, new research shows.

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A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.

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Awarded the 2023 Nobel Prize in Chemistry, quantum dots have a wide variety of applications ranging from displays and LED lights to chemical reaction catalysis and bioimaging. These semiconductor nanocrystals are so small -- on the order of nanometers -- that their properties, such as color, are size dependent, and they start to exhibit quantum properties. This technology has been really well developed, but only in the visible spectrum, leaving untapped opportunities for technologies in both the ultraviolet and infrared regions of the electromagnetic spectrum.

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Certain types of light have proven to be an effective, minimally invasive treatment for cancers located on or near the skin when combined with a light-activated drug. But deep-seated cancers have been beyond the reach of light's therapeutic effects. To change this, engineers and scientists have devised a wireless LED device that can be implanted. This device, when combined with a light-sensitive dye, not only destroys cancer cells, but also mobilizes the immune system's cancer-targeting response.

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Development of a new way to accurately measure human serum albumin (HSA) levels in people with chronic kidney disease has progressed in recent testing.

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A small molecule that naturally serves as a binding site for metals in enzymes also proves useful for separating certain rare earth metals from each other. In a proof of concept, the process extracts europium directly from fluorescent powder in used energy-saving lamps in much higher quantities than existing methods. The researchers are now working on expanding their approach to other rare earth metals. They are in the process of founding a start-up to put the recycling of these raw materials into practice.

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Ice in nature is surrounded by liquid most of the time, and therefore it is key to understand how ice and liquid interact. A new study has now directly observe the precise shape of ice at the interface between ice and liquid -- by using antifreeze and a refrigerated microscope.

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Is it possible to create a new class of materials from very different substances using the 'one-pot synthesis' approach? Chemists explain how they enable the synthesis of such novel materials.

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In a study involving 50,000+ individuals from around the world, higher gut levels of Blastocystis, a single-celled organism commonly found in the digestive system, were linked to more favorable indicators of health.

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A study of ancient dingo DNA revealed that the distribution of modern dingoes across Australia, including those on K'gari (formerly Fraser Island), pre-dates European colonization and interventions like the dingo-proof fence.

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Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.

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Researchers have identified hexagonal perovskite-related oxides as materials with exceptionally high proton conductivity and thermal stability. Their unique crystal structure and large number of oxygen vacancies enable full hydration and high proton diffusion, making these materials ideal candidates as electrolytes for next-generation protonic ceramic fuel cells that can operate at intermediate temperatures without degradation.

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Genotyping techniques can be used to select fruit trees with desired traits at the seedling stage, increasing the efficiency of fruit tree breeding. However, so far, there are multiple different genotyping systems, each generating distinct datasets. In a recent study, Japanese scientists revealed that integrating genomic data obtained with different genotyping systems can effectively combine with historical data, leveraging the accuracy of genomic predictions.

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Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, scientists report. By integrating this method with time-resolved serial femtosecond crystallography, they successfully visualized reaction dynamics and rapid structural changes occurring within reaction centers immobilized inside protein crystals. This innovative strategy holds significant potential for the intelligent design of drugs, catalysts, and functional materials.

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Researchers have developed a discovery platform to probe the function of genes involved in metabolism -- the sum of all life-sustaining chemical reactions. The investigators used the new platform, called GeneMAP (Gene-Metabolite Association Prediction), to identify a gene necessary for mitochondrial choline transport.