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Categories: Biology: Genetics, Chemistry: Organic Chemistry
Published 'Shocking' discovery: Electricity from electric eels may transfer genetic material to nearby animals



Researchers have discovered that electric eels can alter the genes of tiny fish larvae with their electric shock. Their findings help to better understand electroporation, a method by which genes can be transported using electricity.
Published Sugar permeation discovered in plant aquaporins



Aquaporins, which move water through membranes of plant cells, were not thought to be able to permeate sugar molecules, but researchers have observed sucrose transport in plant aquaporins for the first time, challenging this theory.
Published Macrophages 'eat' insulin-producing cells to regulate insulin after mice have given birth



Pregnancy brings a rise in pancreatic beta cells -- the cells that produce insulin. Shortly after birth, these cells return to their normal levels. The mechanisms behind this process had remained a mystery. But now a research group has revealed that white blood cells called macrophages 'eat' these cells.
Published Researchers decode aqueous amino acid's potential for direct air capture of CO2



Scientists have made a significant stride toward understanding a viable process for direct air capture, or DAC, of carbon dioxide from the atmosphere. This DAC process is in early development with the aim of achieving negative emissions, where the amount of carbon dioxide removed from the envelope of gases surrounding Earth exceeds the amount emitted.
Published More than 100 'magic mushroom' genomes point the way to new cultivars



Scientists have amassed genome data for dozens of 'magic mushroom' isolates and cultivars, with the goal to learn more about how their domestication and cultivation has changed them. The findings may point the way to the production of intriguing new cultivars, say the researchers.
Published Researchers have cracked the cellular code on protein folding, offering hope for new therapeutic avenues for many diseases



While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins. A team of researchers recently leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.
Published New technique efficiently offers insight into gene regulation



Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.
Published PicoRuler: Molecular rulers for high-resolution microscopy



A team presents a groundbreaking advance for the world of high-resolution fluorescence microscopy: The innovative method enables researchers for the first time to use biomolecules as molecular rulers to calibrate the latest super-resolution microscopy methods, which have a resolution of just a few nanometers.
Published Genomic study sheds light on how carnivorous Asian pitcher plants acquired signature insect trap



Scientists sequenced the genome of the East Asian pitcher plant, Nepenthes gracilis, a species of carnivorous plant related to Venus flytraps, as well as sundews, beets and spinach.
Published Researchers reveal new process for making anhydride chemical compounds



A collaborative research team has discovered a new process for making anhydrides that promises improvements in costs and sustainability.
Published A mixed origin made maize successful



Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.
Published Clever dosage control mechanism of biallelic genes



Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Published Key protein in blood vessel's growth identified



New research identifies the class II PI3K-C2b protein, a member of the PI3 family of kinases, as one of the key regulators of blood vessels growth in humans and other mammals. Mutations in these family of proteins may lead to vascular malformations and the precise understanding of the whole process is instrumental in opening the door to new therapeutic approaches in the future.
Published Artificial intelligence paves way for new medicines



Researchers have developed an AI model that can predict where a drug molecule can be chemically altered.
Published Researchers decipher enzyme scissors of intestinal microbes



Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).
Published Releasing brakes on biocatalysis



Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published The venom preceded the stinger: Genomic studies shed light on the origins of bee venom



Bees, wasps and ants belong to the Hymenoptera order and inject a whole cocktail of venomous ingredients when they sting. Despite their tremendous ecological and economic importance, little was previously known about the origins of their venom. Through extensive genomic studies, a team of researchers has now discovered that typical venomous components were already present in the earliest ancestors of Hymenoptera and must therefore have evolved before the stingers of bees and other insects. What's more, and contrary to previous assumptions, the gene for the venom melittin is found solely in bees.
Published Greener solution powers new method for lithium-ion battery recycling



Used lithium-ion batteries from cell phones, laptops and a growing number of electric vehicles are piling up, but options for recycling them remain limited mostly to burning or chemically dissolving shredded batteries. Researchers have improved on approaches that dissolve the battery in a liquid solution in order to reduce the amount of hazardous chemicals used in the process. This simple, efficient and environmentally-friendly solution overcomes the main obstacles presented by previous approaches.
Published Tracing the evolution of the 'little brain'



The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published Scientists harness flower 'super power' to pave the way for new drug treatments



Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.