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Categories: Biology: Genetics, Energy: Nuclear
Published The genetic 'switches' of bone growth
(via sciencedaily.com) Original source In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.
Published Sweaty cattle may boost food security in a warming world
(via sciencedaily.com) Original source Climate change is making it more difficult to raise cattle -- growth and reproduction are affected by heat -- so it's critical to breed cattle better adapted to a hotter and longer summer. A new study shows it's possible to identify the genes within breeds of cattle that would lead to the sweatiest, heat-tolerant offspring.
Published Pair plasmas found in deep space can now be generated in the lab
(via sciencedaily.com) Original source Researchers have experimentally generated high-density relativistic electron-positron pair-plasma beams by producing two to three orders of magnitude more pairs than previously reported.
Published Modifying genomes of tardigrades to unravel their secrets
(via sciencedaily.com) Original source Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. Researchers have now successfully edited genes using the CRISPR technique in a highly resilient tardigrade species previously impossible to study with genome-editing tools. The successful delivery of CRISPR to an asexual tardigrade species directly produces gene-edited offspring. The design and editing of specific tardigrade genes allow researchers to investigate which are responsible for tardigrade resilience and how such resilience can work.
Published The gender gap in life expectancy: Are eggs and sperm partly responsible?
(via sciencedaily.com) Original source Researchers have found that germ cells, which develop into eggs and sperm, drive sex-dependent differences in lifespan in vertebrates. Female and male germ cells increase and reduce lifespan, respectively. These effects are controlled via estrogen and growth factor hormones in females and vitamin D in males. Vitamin D supplementation extends lifespan in both males and females. The results clarify the link between reproduction and aging and show that vitamin D may improve longevity in vertebrates.
Published Metal alloys that can take the heat
(via sciencedaily.com) Original source Complex metal alloys enter a new era of predictive design for aerospace and other high-temperature applications.
Published New technique reveals earliest signs of genetic mutations
(via sciencedaily.com) Original source Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including cancer. Now, a new study introduces an original technique, called HiDEF-seq, that can accurately detect the early molecular changes in DNA code that precede mutations.
Published Scientists engineer yellow-seeded camelina with high oil output
(via sciencedaily.com) Original source Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates 21.4% more oil than ordinary camelina.
Published New plasma escape mechanism could protect fusion vessels from excessive heat
(via sciencedaily.com) Original source The exhaust heat generated by a fusing plasma in a commercial-scale reactor may not be as damaging to the vessel's innards as once thought, according to new research about escaping plasma particles.
Published Virus-like nanoparticles control the multicellular organization and reproduction of host bacteria
(via sciencedaily.com) Original source Researchers have discovered that virus-like nanoparticles can promote the multicellular organization and reproduction of host bacteria. These particles, which are evolutionarily related to phages (viruses that infect bacteria), contain an enzyme that helps shape the multicellular architecture and ultimately enhances morphological differentiation.
Published Algae offer real potential as a renewable electricity source
(via sciencedaily.com) Original source The need to transition away from fossil fuels to more sustainable energy production is critical. That's why a team of researchers is looking at a potential power source that not only produces no carbon emissions but removes carbon as it works: algae.
Published Protein study could help researchers develop new antibiotics
(via sciencedaily.com) Original source A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions.
Published Fine-tuning leaf angle with CRISPR improves sugarcane yield
(via sciencedaily.com) Original source A CABBI research team has used CRISPR/Cas9 gene editing to optimize leaf angle in sugarcane, increasing the amount of sunlight it captures and the amount of biomass it produces.
Published How human derived RNA fragments help the Hepatitis E virus
(via sciencedaily.com) Original source Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.
Published Novel Genetic Clock discovers oldest known marine plant
(via sciencedaily.com) Original source An international research team has discovered the oldest known marine plant using a novel genetic clock. This 1400-year-old seagrass clone from the Baltic Sea dates back to the Migration Period. The research project is a significant step towards better understanding and protecting marine ecosystems.
Published A protein that enables smell--and stops cell death
(via sciencedaily.com) Original source While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.
Published Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time
(via sciencedaily.com) Original source Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
Published Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease
(via sciencedaily.com) Original source By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.
Published Silkworms help grow better organ-like tissues in labs
(via sciencedaily.com) Original source Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.
Published Scientists 'read' the messages in chemical clues left by coral reef inhabitants
(via sciencedaily.com) Original source What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex 'soup' that is hard for scientists to decipher. Now, researchers have demonstrated a way to extract and identify these indicator compounds in seawater. They found metabolites previously undetected on reefs, including three that may represent different reef organisms.