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Categories: Biology: Genetics, Physics: Quantum Physics

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A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.

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True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.

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Physicists have shown that simulating models of hypothetical time travel can solve experimental problems that appear impossible to solve using standard physics.

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To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.

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Researchers have long been exploring the effect of using tailored laser drives to manipulate the properties of quantum materials away from equilibrium. One of the most striking demonstrations of these physics has been in unconventional superconductors, where signatures of enhanced electronic coherences and super-transport have been documented in the resulting non-equilibrium states. However, these phenomena have not yet been systematically studied or optimized, primarily due to the complexity of the experiments. Technological applications are therefore still far removed from reality. In a recent experiment, this same group of researchers discovered a far more efficient way to create a previously observed metastable, superconducting-like state in K3C60 using laser light.

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Researchers have obtained new insights into how African-American and Hispanic-American people’s genes influence their ability to use Omega-3 and Omega-6 fatty acids for good health. The findings are an important step toward “precision nutrition” – where a diet tailored to exactly what our bodies need can help us live longer, healthier lives.

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A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'  

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Relationship patterns among flightless stick insects suggest that birds disperse the eggs after eating gravid females. Lab experiments previously suggested the possibility, but a new genetic analysis of natural populations in Japan now supports the idea.

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Understanding the interplay between consciousness, energy and matter could bring important insights to our fundamental understanding of reality.

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The interaction between solid matter and positron (the antiparticle of electron) has provided important insights across a variety of disciplines, including atomic physics, materials science, elementary particle physics, and medicine. However, the experimental generation of positronic compounds by bombardment of positrons onto surfaces has proved challenging. In a new study, researchers detect molecular ion desorption from the surface of an ionic crystal when bombarded with positrons and propose a model based on positronic compound generation to explain their results.

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A study found that a new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel.

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Researchers have unveiled a new mechanism for regulating mitochondrial function. The findings reveal the critical role played by the enzymatic activity of the lysine acetyltransferase MOF in maintaining mitochondrial integrity and function through acetylation of mitochondrial electron transport chain component COX17. Cells lacking MOF-mediated COX17 acetylation exhibit dramatic mitochondrial defects and impaired ability to produce energy. Underscoring the clinical relevance of these findings, the team also showed that cells from human patients with a developmental disorder caused by mutations in MOF also exhibited respiratory defects that could be ameliorated by interventions such as acetylation-mimetic COX17 or mitochondrially targeted MOF.

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Researchers have discovered the master regulator responsible for balancing the expression of X chromosome genes between males and females in the malaria mosquito. This discovery helps scientists better understand the evolution of the epigenetic mechanisms responsible for equalizing gene expression between the sexes. The findings may contribute to the development of new ways to prevent the spread of malaria.

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Grass may transfer genes from their neighbors in the same way genetically modified crops are made, a new study has revealed.   

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Researchers have developed a 'quantum ruler' to measure and explore the strange properties of multilayered sheets of graphene, a form of carbon. The work may also lead to a new, miniaturized standard for electrical resistance that could calibrate electronic devices directly on the factory floor, eliminating the need to send them to an off-site standards laboratory.   

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Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.

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Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.  

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Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.

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Despite decades of decline, a genetic analysis of ruffed grouse reveals that Pennsylvania's state bird harbors more genetic diversity and connectivity than expected. The findings suggest that the iconic game bird could be maintained in persistent numbers if appropriate protections are implemented.

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A person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new study has found. The findings open the door to further studies that could have important implications regarding dietary recommendations and the production of meat substitutes.