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Categories: Biology: Genetics, Physics: Acoustics and Ultrasound

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Haptic holography promises to bring virtual reality to life, but a new study reveals a surprising physical obstacle that will need to be overcome.

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A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.

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A detailed atlas of gene expression in the zebrafish brain.

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A new device that calms overactive kidney nerves with ultrasound consistently lowered blood pressure in patients with uncontrolled hypertension, researchers have found.

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Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred.

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By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.

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Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.

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Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.

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A research team presents technology that enhances photoacoustic computed tomography using a deep-learning approach.

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Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingredients are needed. Important findings in this regard have been provided: for the virus to proliferate, the polymerase of the influenza A virus has to be modified many times through enzymes in the host cells. The team of researchers was able to produce a comprehensive map of types of modification. Medicines directed against the enzymes woud be resilient to rapid mutations in the virus, thus offering great potential for the future.

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A team has developed a method for selectively manipulating genetically engineered cells with ultrasound.

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Growing wheat in drought conditions may be easier in the future. Researchers found the right number of copies of a specific group of genes can stimulate longer root growth, enabling wheat plants to pull water from deeper supplies.

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Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study.

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High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data. The visualization, analysis and dissemination of such large imaging data sets poses significant challenges. Now, these tasks can be carried out using MoBIE, which stands for Multimodal Big Image Data Exploration, a new user-friendly, freely available tool. This means that researchers such as biologists, who rely on high-resolution microscopy techniques, can incorporate multiple data sets to study the processes of life at the very smallest scales.

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It was the height of summer 2022 when the calls started coming in. Scores of dead deer suddenly littered rural properties and park preserves, alarming the public and inconveniencing landowners. According to officials at the Urbana Park District, it was Epizootic Hemorrhagic Disease (EHD), a midge-borne viral illness that pops up in white-tailed deer populations around the state every few years. And when susceptible deer are infected, they die within days. Now, scientists have found gene variants in deer associated with the animals' susceptibility to EHD.

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New research sheds light on how electric fields can be used to alter the thermal properties of ferroelectric materials, allowing engineers to manipulate the flow of heat through the materials. Ferroelectric materials are used in a wide variety of applications, from ultrasound devices to memory storage technologies.

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Researchers have developed the first smart wearable device to continuously track how much people use their voices, alerting them to overuse before vocal fatigue and potential injury set in. The soft, flexible, postage-stamp-sized device comfortably adheres to the upper chest to sense the subtle vibrations associated with talking and singing. From there, the captured data is instantaneously streamed via Bluetooth to the users' smartphone or tablet, so they can monitor their vocal activities in real time throughout the day and measure cumulative total vocal usage. Custom machine-learning algorithms distinguish the difference between speaking and singing, enabling singers to separately track each activity.

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When the Artemis 1 mission was launched in November, it became the world's most powerful rocket, and with liftoff came a loud roar heard miles away. Researchers report noise measurements during the launch at different locations around Kennedy Space Center. The data collected can be used to validate existing noise prediction models, which are needed to protect equipment as well as the surrounding environment and community.

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Scientists have created a new technology to assemble matter in 3D. Their concept uses multiple acoustic holograms to generate pressure fields with which solid particles, gel beads and even biological cells can be printed. These results pave the way for novel 3D cell culture techniques with applications in biomedical engineering.

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New research found that using focused-ultrasound-mediated liquid biopsy in a mouse model released more tau proteins and another biomarker into the blood than without the intervention. This noninvasive method could facilitate diagnosis of neurodegenerative disorders, the researchers said.