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Categories: Biology: Genetics, Physics: Acoustics and Ultrasound
Published Metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
(via sciencedaily.com) Original source Mice that received fecal implants from donors that had their ovaries removed gained more fat mass and had greater expression of liver genes associated with inflammation, Type 2 diabetes, fatty liver disease and atherosclerosis. The findings may shed light on the greater incidence of metabolic dysfunction in postmenopausal women.
Published Damage to cell membranes causes cell aging
(via sciencedaily.com) Original source Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Published Butterfly and moth genomes mostly unchanged despite 250 million years of evolution
(via sciencedaily.com) Original source Comparison of over 200 high-quality butterfly and moth genomes reveals key insights into their biology, evolution and diversification over the last 250 million years, as well as clues for conservation.
Published An awkward family reunion: Sea monsters are our cousins
(via sciencedaily.com) Original source The sea lamprey, a 500-million-year-old animal with a sharp-toothed suction cup for a mouth, is the thing of nightmares. A new study discovered that the hindbrain -- the part of the brain controlling vital functions like blood pressure and heart rate -- of both sea lampreys and humans is built using an extraordinarily similar molecular and genetic toolkit.
Published New system triggers cellular waste disposal
(via sciencedaily.com) Original source Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders
(via sciencedaily.com) Original source Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.
Published Photosynthetic mechanism of purple sulfur bacterium adapted to low-calcium environments
(via sciencedaily.com) Original source Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.
Published Researchers are using RNA in a new approach to fight HIV
(via sciencedaily.com) Original source A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
Published Eating too much protein is bad for your arteries, and this amino acid is to blame
(via sciencedaily.com) Original source Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.
Published Toxoplasmosis: Evolution of infection machinery
(via sciencedaily.com) Original source Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.
Published Asexual propagation of crop plants gets closer
(via sciencedaily.com) Original source When the female gametes in plants become fertilized, a signal from the sperm activates cell division, leading to the formation of new plant seeds. This activation can also be deliberately triggered without fertilization, as researchers have shown. Their findings open up new avenues for the asexual propagation of crop plants.
Published Root microbes may be the secret to a better tasting cup of tea
(via sciencedaily.com) Original source You'd think the complex flavor in a quality cup of tea would depend mainly on the tea varieties used to make it. But a new study shows that the making of a delicious cup of tea depends on another key ingredient: the collection of microbes found on tea roots. By altering that assemblage, the authors showed that they could make good-quality tea even better.
Published Ancient retroviruses played a key role in the evolution of vertebrate brains
(via sciencedaily.com) Original source Researchers report that ancient viruses may be to thank for myelin -- and, by extension, our large, complex brains. The team found that a retrovirus-derived genetic element or 'retrotransposon' is essential for myelin production in mammals, amphibians, and fish. The gene sequence, which they dubbed 'RetroMyelin,' is likely a result of ancient viral infection, and comparisons of RetroMyelin in mammals, amphibians, and fish suggest that retroviral infection and genome-invasion events occurred separately in each of these groups.
Published Team creates novel rabies viral vectors for neural circuit mapping
(via sciencedaily.com) Original source A research team has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer's disease brain neurons.
Published Key genes linked to DNA damage and human disease uncovered
(via sciencedaily.com) Original source Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.
Published Researchers uncover mechanisms behind enigmatic shapes of nuclei
(via sciencedaily.com) Original source White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens. Scientists have now deciphered the shapeshifting puzzle of the neutrophil nucleus.
Published New understanding of avian eggshell attachment -- implications for medical procedures and egg industry
(via sciencedaily.com) Original source Athletes often suffer injuries to ligaments in their knees, particularly to the anterior cruciate ligament or ACL. While surgery to replace these torn ligaments is becoming increasingly common around the world it often needs to be repeated. That's because it has proved challenging to anchor fibrous, soft and wet ligament grafting material into hard bone. Now, researchers have new information from the eggshell membrane in chicken eggs that could help change this picture thanks to the potential it offers for improvements in tissue engineering and biomaterial grafts. Their findings also have the potential to reduce losses for commercial egg and poultry producers.
Published Fundamental equation for superconducting quantum bits revised
(via sciencedaily.com) Original source Physicists have uncovered that Josephson tunnel junctions -- the fundamental building blocks of superconducting quantum computers -- are more complex than previously thought. Just like overtones in a musical instrument, harmonics are superimposed on the fundamental mode. As a consequence, corrections may lead to quantum bits that are 2 to 7 times more stable. The researchers support their findings with experimental evidence from multiple laboratories across the globe.
Published By growing animal cells in rice grains, scientists dish up hybrid food
(via sciencedaily.com) Original source From lab-grown chicken to cricket-derived protein, these innovative alternatives offer hope for a planet struggling with the environmental and ethical impacts of industrial agriculture. Now, scientists add a new recipe to the list -- cultured beef rice -- by growing animal muscle and fat cells inside rice grains. The method results in a nutritious and flavorful hybrid food that, once commercialized, could offer a more affordable protein alternative with a smaller carbon footprint.
Published Controlling root growth direction could help save crops and mitigate climate change
(via sciencedaily.com) Original source Scientists have determined how the well-known plant hormone ethylene is crucial in controlling the angle at which roots grow. The findings can be used to engineer plants and crops that withstand the environmental stresses of climate change and drought, and perhaps to create plants that remove carbon dioxide from the atmosphere and store it deep underground to help mitigate climate change.