Showing 20 articles starting at article 721

< Previous 20 articles        Next 20 articles >

Categories: Biology: Genetics, Physics: Acoustics and Ultrasound

Return to the site home page

     (via sciencedaily.com)     Original source 

Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

     (via sciencedaily.com) 

The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.

     (via sciencedaily.com)     Original source 

Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. A team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called 'diazotrophs.' These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria.

     (via sciencedaily.com)     Original source 

Scientists have discovered a simple and reliable test for signs of past or present life on other planets -- 'the holy grail of astrobiology.' Researchers report that, with 90% accuracy, their artificial intelligence-based method distinguished modern and ancient biological samples from those of abiotic origin.

     (via sciencedaily.com)     Original source 

Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms underlying the disease, and offers new tools for their prevention.

     (via sciencedaily.com)     Original source 

Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.

     (via sciencedaily.com) 

Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.

     (via sciencedaily.com) 

To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.

     (via sciencedaily.com)     Original source 

Living things from plants to humans must constantly adjust the chemical soup of proteins -- the workhorse molecules of life -- inside their cells to adapt to stress or changing conditions. Now, researchers have identified a previously unknown molecular mechanism that helps explain how they do it. A team now reveals hairpin-like structures of mRNA that, by zipping and unzipping, help cells change the mix of proteins they produce when under stress.

     (via sciencedaily.com) 

A team has developed a shape-changing smart speaker, which uses self-deploying microphones to divide rooms into speech zones and track the positions of individual speakers.

     (via sciencedaily.com)     Original source 

Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.

     (via sciencedaily.com)     Original source 

Biologists have discovered why an enzyme is important for the survival of fruit flies, even though it can shorten their lives under certain conditions.

     (via sciencedaily.com) 

Using engineered microbes as microscopic factories has given the world steady sources of life-saving drugs, revolutionized the food industry, and allowed us to make sustainable versions of valuable chemicals previously made from petroleum. But behind each biomanufactured product on the market today is the investment of years of work and many millions of dollars in research and development funding. Scientists want to help the burgeoning industry reach new heights by accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.

     (via sciencedaily.com)     Original source 

Scientists have found a plant gene that drives the growth of root hairs, the tiny structures that help plants find water and nutrients in the soil. The gene, dubbed 'BUZZ,' causes faster-growing, denser webs of roots and may also determine how plants find and use nitrates, a prime source of nitrogen essential to plant growth. Nitrates are also used in fertilizers that can pollute the environment as runoff, and this genetic discovery could ultimately help plant scientists find ways to grow crops more sustainably.

     (via sciencedaily.com) 

Researchers have developed a way of detecting the early onset of deadly infectious diseases using a test so ultrasensitive that it could someday revolutionize medical approaches to epidemics. The test is an electronic sensor contained within a computer chip. It employs nanoballs -- microscopic spherical clumps made of tinier particles of genetic material -- and combines that technology with advanced electronics.

     (via sciencedaily.com)     Original source 

A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.

     (via sciencedaily.com)     Original source 

A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the woolly mammoth, as well as for studying pandemic RNA viruses.

     (via sciencedaily.com)     Original source 

Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.

     (via sciencedaily.com)     Original source 

Tweaks to the mitochondrial genome hold the potential for better hybrid seed production or to introduce seedless fruits.

     (via sciencedaily.com)     Original source 

Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.