Showing 20 articles starting at article 801

< Previous 20 articles        Next 20 articles >

Categories: Biology: Genetics, Physics: Acoustics and Ultrasound

Return to the site home page

     (via sciencedaily.com)     Original source 

Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.

     (via sciencedaily.com)     Original source 

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.

     (via sciencedaily.com)     Original source 

Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.

     (via sciencedaily.com)     Original source 

An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.

     (via sciencedaily.com)     Original source 

Porous media such as concrete physically represent a spherical packing of different components -- in this case cement, rock and water. The mechanical properties of such mixtures are still difficult to calculate due to their discretized nature. A team has now been able to investigate an unexpected property of mixtures of granular media consisting of soft and stiff spherical particles. For this purpose, a combination of ultrasound investigations and X-ray computed tomographic imaging was employed, allowing a three-dimensional (3D) characterization and evaluation. The discovery could contribute to safer future building in earthquake zones.

     (via sciencedaily.com)     Original source 

For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.

     (via sciencedaily.com)     Original source 

Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.

     (via sciencedaily.com)     Original source 

DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.

     (via sciencedaily.com)     Original source 

Researchers have discovered that extracts from plants used by the Kwakwaka'wakw First Nations peoples in their traditional botanical medicine practices are able to rescue the function of ion channel proteins carrying mutations that cause human Episodic Ataxia.

     (via sciencedaily.com)     Original source 

Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.

     (via sciencedaily.com)     Original source 

Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.

     (via sciencedaily.com)     Original source 

A detailed, high-resolution map of the rusty patched bumble bee's genome has been released, offering new approaches for bringing the native pollinator back from the danger of extinction. Putting together the rusty patched bumble bee genome is part of the Beenome 100 project, a first-of-its-kind effort to create a library of high-quality, highly detailed genome maps of 100 or more diverse bee species found in the United States.

     (via sciencedaily.com)     Original source 

In the face of the biodiversity crisis, and alarming data showing a 69% decline in global animal populations since 1970, researchers are banking on a cool solution to help save species from extinction. Much like egg-freezing is used to preserve human fertility options for a later date, the cryo-freezing of genetic samples taken from animals may play an essential role in curbing species extinctions. A new study sheds light on the immense potential of living cell banks, also known as cryobanks, to contribute to global conservation priorities.

     (via sciencedaily.com)     Original source 

Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.

     (via sciencedaily.com)     Original source 

Biologists provide evidence for an alternative genetic mechanism that can lead to plants becoming self-pollinators.

     (via sciencedaily.com)     Original source 

Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.

     (via sciencedaily.com)     Original source 

A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.

     (via sciencedaily.com)     Original source 

To ensure that wounds remain tightly sealed in the abdomen after surgery, researchers have developed a patch with a sensor function. The polymer patch warns before the occurrence of dangerous leaks on sutures in the gastrointestinal tract take hold, while closes the areas on its own. A new material now enables a fast, easy and non-invasive leak diagnosis.

     (via sciencedaily.com)     Original source 

A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.

     (via sciencedaily.com)     Original source 

Researchers have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections. Their research findings can inform the development of future treatments for life-threatening acute infections.