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Categories: Biology: Genetics, Computer Science: Encryption
Published Scientists uncover new way viruses fight back against bacteria



A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.
Published New insights into the genetics of the common octopus: Genome at the chromosome level decoded



Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.
Published Greener neighborhoods can protect us -- at the cellular level



A new study finds that greenspace -- the vegetation in a neighborhood's yards, parks and public spaces -- has a positive impact on a key genetic marker associated with exposure to stress. However, the study also finds that the positive impact of greenspace isn't enough to compensate for other environmental challenges, such as air pollution.
Published Unlocking the secrets of cell behavior on soft substrates: A paradigm shift in mechanobiology



A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.
Published Whaling wiped out far more fin whales than previously thought



Whaling in the 20th century destroyed 99% of the Eastern North Pacific fin whale breeding population. Because there is enough genetic diversity, current conservation measures should help the population rebound without becoming inbred. The future of fin whales in the Gulf of California depends on the recovery of the Eastern North Pacific population.
Published Critical step made for managing brushtail possums



Researchers say mapping the genetic code of the brushtail possum will benefit those working to both conserve and control the animal.
Published Unlocking secrets of immune system proteins: A potential path to new treatments



Using cryo-electron microscopy (cryo-EM), researchers captured unprecedented images of key immune system receptors interacting with messenger proteins, elucidating how the receptors change shape upon activation and transmit signals within the cell. The findings suggest new pathways for developing therapeutic molecules for diseases such as COVID-19, rheumatoid arthritis, neurodegenerative diseases and cancer.
Published Boosting weak immune system: Scientists find an unusual weapon against virus



Infections with cytomegalovirus (CMV) are extremely common and often pose no major threat to the vast majority of people. They can however be deadly for people whose immune system is weakened, e.g., after bone marrow transplantation. Current treatments against CMV infections are very limited and can have severe side effects. Researchers now propose a new way to protect against CMV. Instead of targeting the virus, their approach boosts the weak immune system and lets it fight the virus on its own.
Published Scientists discover the possible triggers for bacterial pathogens, opening the door for new treatment strategies



The legendary Alexander Fleming, who famously discovered penicillin, once said 'never to neglect an extraordinary appearance or happening.' And the path of science often leads to just that. New research is turning the page in our understanding of harmful bacteria and how they turn on certain genes, causing disease in our bodies.
Published Genomic analysis in snakes shows link between neutral, functional genetic diversity



In the world of threatened and endangered species conservation, the genomic revolution has raised some complicated questions: How can scientists justify assessing species genetic diversity without consulting entire genomes now that they can be sequenced? But then again, how can scientists justify the time and expense of genome sequencing when age-old measures of neutral genetic diversity are much cheaper and easier to obtain? A new study suggests making a transition from 'old school' genetics to 'new school' genomics for species conservation purposes probably isn't necessary in all cases.
Published Fungal infection in the brain produces changes like those seen in Alzheimer's disease



Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.
Published Can't stop binging on fries and BBQ?



People overeat and become overweight for a variety of reasons. The fact that flavorful high-calorie food is often available nearly everywhere at any time doesn't help. Researchers have determined for the first time why certain chemicals in cooked or processed foods, called advanced glycation end products, or AGEs, increase hunger and test our willpower or ability to make healthy choices when it comes to food.
Published Peering inside cells to see how they respond to stress



The heat shock response of cells is a classic model of biological adaptation, part of the fundamental processes of life -- conserved in creatures from single-celled yeast to humans -- that allow our cells to adjust to changing conditions in their environment. For years, scientists have focused on how different genes respond to heat stress to understand this survival technique. Now, thanks to the innovative use of advanced imaging techniques, researchers are getting an unprecedented look at the inner machinery of cells to see how they respond to heat stress.
Published Climate change coping mechanism discovered in humble algae



One of the building blocks of ocean life can adapt to cope with the effects of climate change, according to new research. The discovery holds promises for biotechnology developments that could counter the negative effects of changing environmental conditions, such as ocean warming and even the reduction in the productivity of crops.
Published Fecal microbe transplants: B. vulgatus genes that correlate with early colonization



Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant. Most failures of fecal microbe transplantation occur in the first four weeks. Researchers have now found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.
Published 200-year-old DNA helps map tiny fly's genetic course to new lands, modern times



Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.
Published Scientists generate first single-cell 'atlas' of the primate brain to help explore links between molecules, cells, brain function and disease



As part of the effort to better understand the evolution of the brains in people and animals, a research team has generated the world's largest primate brain-wide atlas.
Published Scientists unveil detailed cell maps of the human brain and the nonhuman primate brain



A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.
Published Honey bees may inherit altruistic behavior from their mothers



True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.
Published Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method



To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.