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Categories: Biology: Genetics, Computer Science: Encryption
Published Cryo conservation: A cool solution to saving species from extinction



In the face of the biodiversity crisis, and alarming data showing a 69% decline in global animal populations since 1970, researchers are banking on a cool solution to help save species from extinction. Much like egg-freezing is used to preserve human fertility options for a later date, the cryo-freezing of genetic samples taken from animals may play an essential role in curbing species extinctions. A new study sheds light on the immense potential of living cell banks, also known as cryobanks, to contribute to global conservation priorities.
Published A new tool to study complex genome interactions



Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.
Published From cross to self-pollination



Biologists provide evidence for an alternative genetic mechanism that can lead to plants becoming self-pollinators.
Published Tethering of shattered chromosomal fragments paves way for new cancer therapies



Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.
Published Close up on aging reveals how different cell types in the body age at different pace



A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Elimination of type of bacteria suggests treatment for endometriosis



A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Scientists discover small RNA that regulates bacterial infection



Researchers have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections. Their research findings can inform the development of future treatments for life-threatening acute infections.
Published Scientists investigate the evolution of animal developmental mechanisms, show how some of Earth's earliest animals evolved



Lacking bones, brains, and even a complete gut, the body plans of simple animals like sea anemones appear to have little in common with humans and their vertebrate kin. Nevertheless, new research shows that appearances can be deceiving, and that a common genetic toolkit can be deployed in different ways to drive embryological development to produce very different adult body plans. It is well established that sea anemones, corals, and their jellyfish relatives shared a common ancestor with humans that plied the Earth's ancient oceans over 600 million years ago. A new study from the Gibson Lab, published in Current Biology on June 13, 2023, illuminates the genetic basis for body plan development in the starlet sea anemone, Nematostella vectensis. This new knowledge paints a vivid picture of how some of the earliest animals on earth progressed from egg to embryo to adult.
Published New method traces ancestry of hybrid plants and animals



Hybrid plants and animals have complicated genomes. A biologist has discovered a way to reveal their parent species.
Published CRISPR/Cas9-based gene drive could suppress agricultural pests



Researchers have now used a gene-drive system to suppress an important agricultural pest.
Published When water temperatures change, the molecular motors of cephalopods do too



Working with live squid hatchlings, scientists find the animals can tune their proteome on the fly in response to changes in ocean temperature via the unique process of RNA recoding. The findings inspire new questions about basic protein function.
Published Study unravels the mysteries of actin filament polarity



An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles.
Published Octopuses rewire their brains to adapt to seasonal temperature shifts



Octopuses don't thermoregulate, so their powerful brains are exposed to -- and potentially threatened by -- changes in temperature. Researchers report that two-spot octopuses adapt to seasonal temperature shifts by producing different neural proteins under warm versus cool conditions. The octopuses achieve this by editing their RNA, the messenger molecule between DNA and proteins. This rewiring likely protects their brains, and the researchers suspect that this unusual strategy is used widely amongst octopuses and squid.
Published Remains of an extinct world of organisms discovered



Newly discovered biomarker signatures point to a whole range of previously unknown organisms that dominated complex life on Earth about a billion years ago. They differed from complex eukaryotic life as we know it, such as animals, plants and algae in their cell structure and likely metabolism, which was adapted to a world that had far less oxygen in the atmosphere than today.
Published Older trees accumulate more mutations than their younger counterparts



A study of the relationship between the growth rate of tropical trees and the frequency of genetic mutations they accumulate suggests that older, long-lived trees play a greater role in generating and maintaining genetic diversity than short-lived trees.
Published A compound from fruit flies could lead to new antibiotics



Research shows that the natural peptide, called drosocin, protects fruit flies from bacterial infections by binding to ribosomes in bacteria. Once bound, drosocin prevents the ribosome from making new proteins.
Published CRISPR/Cas9 reveals a key gene involved in the evolution of coral skeleton formation



New work uses cutting-edge CRISPR/Cas9 genome editing tools to reveal a gene that's critical to stony corals' ability to build their reef architectures. This research could inform coral conservation and restoration efforts.
Published Genomes of 233 primate species sequenced



Researchers from 24 countries have analyzed the genomes of 809 individuals from 233 primate species, generating the most complete catalog of genomic information about our closest relatives to date. The project provides new insights into the evolution of primates, including humans, and their diversity. In baboons, for example, hybridization and gene flow between different species occurred in the past and is still ongoing in several regions of their range. This makes baboons a good model for the evolution of early human lineages within and outside Africa. In addition, using a specially designed AI algorithm, the genomic data enable new insights into the genetic causes of human diseases.
Published New class of antibiotics to fight resistant bacteria



Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.
Published Symbiotic and pathogenic fungi may use similar molecular tools to manipulate plants



Symbiotic and pathogenic fungi that interact with plants are distantly related and don't share many genetic similarities. Comparing plant pathogenic fungi and plant symbiotic fungi, scientists at the Sainsbury Laboratory Cambridge University (SLCU) have discovered that these remote relatives are using a similar group of proteins to manipulate and live within plants.