Biology: Biotechnology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Under pressure: How cells respond to physical stress      (via sciencedaily.com)     Original source 

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.

Biology: Biotechnology Biology: Developmental Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Dual action antibiotic could make bacterial resistance nearly impossible      (via sciencedaily.com)     Original source 

New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.

Biology: Biotechnology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New rapid method for determining virus infectivity      (via sciencedaily.com)     Original source 

A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.

Biology: Developmental Biology: Genetics Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Fruit fly post-mating behavior controlled by male-derived peptide via command neurons, study finds      (via sciencedaily.com)     Original source 

Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.

Biology: Biotechnology Biology: Genetics
Published

New genetic test will eliminate a form of inherited blindness in dogs      (via sciencedaily.com)     Original source 

Scientists have identified the genetic mutation that causes progressive retinal atrophy in English Shepherd Dogs, which results in incurable blindness, and developed a genetic test to help eliminate the disease from future generations of the breed.

Biology: Biotechnology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Exposing dengue's invasion strategies      (via sciencedaily.com)     Original source 

Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.

Biology: Biotechnology Biology: Developmental Biology: Genetics Offbeat: General Offbeat: Plants and Animals
Published

Controlling mosquito populations through genetic breeding      (via sciencedaily.com)     Original source 

Researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides. Their study focused on the genetic basis of species incompatibility. They crossed Ae. aegypti, a major global arboviral disease vector, and its sibling species, Ae. mascarensis, from the Indian Ocean. When offspring is crossed back with one parent, about 10 percent of the progeny becomes intersex and is unable to reproduce.

Biology: Genetics Biology: Molecular
Published

Not everything that tastes bitter is potentially harmful: But why? Study provides an explanation      (via sciencedaily.com)     Original source 

A bitter taste is traditionally considered a warning sign of potentially toxic substances. But not all bitter substances are harmful. For example, some peptides and free amino acids taste bitter, even though they are non-toxic, nutritious and sometimes even vital for humans. A new study now offers an explanation for this seemingly paradoxical phenomenon.

Biology: Biotechnology Biology: Developmental Biology: Genetics Biology: Molecular
Published

Transient structure in fly leg holds clue to insect shape formation      (via sciencedaily.com)     Original source 

A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.

Computer Science: Virtual Reality (VR)
Published

Virtual reality training for physicians aims to heal disparities in Black maternal health care      (via sciencedaily.com)     Original source 

A virtual reality training series being developed for medical students and physicians teaches them about implicit bias in their communications with their patients who are people of color and how that affects race-based health care disparities.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology
Published

The rhythm led by plants is crucial for symbiosis with nutrient-providing bacteria      (via sciencedaily.com)     Original source 

Recent research on Lotus japonicus, a model leguminous plant, has unveiled that the interaction between legume roots and rhizobia is characterized by periodic gene expression with a six-hour rhythm. This rhythmic gene expression influences the regions of the root susceptible to rhizobial infection and the distribution of nodules. It was also discovered that the plant hormone cytokinin is crucial for maintaining this gene expression rhythm.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Geoscience: Geochemistry
Published

Small animals acquire genes from bacteria that can produce antibiotics      (via sciencedaily.com)     Original source 

A group of small, freshwater animals (bdelloid rotifers) protect themselves from infections using antibiotic recipes 'stolen' from bacteria, according to new research. This raises the potential that rotifers are producing novel antimicrobials that may be less toxic to animals, including humans, than those we develop from bacteria and fungi.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Animals
Published

Secrets behind viral precision      (via sciencedaily.com)     Original source 

New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology
Published

Ancient viruses fuel modern-day cancers      (via sciencedaily.com)     Original source 

The human genome is filled with flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago. Scientists used to think they were harmless, but new research shows that, when reawakened, they help cancer survive and thrive.

Biology: Biochemistry Biology: Botany Biology: Evolutionary Biology: General Biology: Genetics Ecology: General Ecology: Invasive Species Ecology: Nature Ecology: Research Ecology: Trees Environmental: Ecosystems Environmental: General
Published

Discovery of a hybrid lineage offers clues to how trees adapt to climate change      (via sciencedaily.com)     Original source 

The discovery of a hybrid population of poplar trees in western Wyoming has provided insight into how natural hybridization informs the evolution of many plant species, according to researchers. They also said their discovery suggests that genetic exchange between species may be critical for adaptation to environmental change.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Paleolithic diets are not without risks      (via sciencedaily.com)     Original source 

High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results suggest caution when following these diets.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Genome recording makes living cells their own historians      (via sciencedaily.com)     Original source 

Genomes can now be used to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft. The method, called ENGRAM, aims to turn cells into their own historians. ENGRAM couples each kind of biological signal or event inside a cell to a symbolic barcode. This new strategy traces and archives the type and timing of biological signals inside the cell by inserting this information into the genome. For example, this record-keeping can track the commands that turn genes on or off.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Ecology: Animals
Published

Influenza viruses can use two ways to infect cells      (via sciencedaily.com)     Original source 

Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells. This ability helps the viruses infect different species -- and potentially jump between animals and humans.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA      (via sciencedaily.com)     Original source 

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.