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Published

It's hearty, it's meaty, it's mold      (via sciencedaily.com)     Original source 

Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New bioengineered protein design shows promise in fighting COVID-19      (via sciencedaily.com)     Original source 

A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.

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Published

New discovery reveals how the egg controls sperm entry      (via sciencedaily.com)     Original source 

After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.

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Published

Even cells know the importance of recycling      (via sciencedaily.com)     Original source 

Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: Water Geoscience: Earth Science Geoscience: Geochemistry Geoscience: Geology
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Sulfur and the origin of life      (via sciencedaily.com)     Original source 

A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Tryptophan in diet, gut bacteria protect against E. coli infection      (via sciencedaily.com)     Original source 

Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.

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Published

New computational strategy boosts the ability of drug designers to target proteins inside the membrane      (via sciencedaily.com)     Original source 

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.

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Published

Staying in the loop: How superconductors are helping computers 'remember'      (via sciencedaily.com)     Original source 

To advance neuromorphic computing, some researchers are looking at analog improvements -- advancing not just software, but hardware too. Research shows a promising new way to store and transmit information using disordered superconducting loops.

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Satellites for quantum communications      (via sciencedaily.com)     Original source 

Through steady advances in the development of quantum computers and their ever-improving performance, it will be possible in the future to crack our current encryption processes. To address this challenge, researchers are developing encryption methods that will apply physical laws to prevent the interception of messages. To safeguard communications over long distances, the QUICK space mission will deploy satellites.

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Published

Simple trick could improve accuracy of plant genetics research      (via sciencedaily.com)     Original source 

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Milk to the rescue for diabetics? Cow produces human insulin in milk      (via sciencedaily.com)     Original source 

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

A simple and robust experimental process for protein engineering      (via sciencedaily.com)     Original source 

A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists find weak points on Epstein-Barr virus      (via sciencedaily.com)     Original source 

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

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Published

How a natural compound from sea squirts combats cancer      (via sciencedaily.com)     Original source 

Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.

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Published

Powerful new tool ushers in new era of quantum materials research      (via sciencedaily.com)     Original source 

Research in quantum materials is paving the way for groundbreaking discoveries and is poised to drive technological advancements that will redefine the landscapes of industries like mining, energy, transportation, and medtech. A technique called time- and angle-resolved photoemission spectroscopy (TR-ARPES) has emerged as a powerful tool, allowing researchers to explore the equilibrium and dynamical properties of quantum materials via light-matter interaction.

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Design rules and synthesis of quantum memory candidates      (via sciencedaily.com)     Original source 

In the quest to develop quantum computers and networks, there are many components that are fundamentally different than those used today. Like a modern computer, each of these components has different constraints. However, it is currently unclear what materials can be used to construct those components for the transmission and storage of quantum information.

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Published

New study reveals transgenerational effects of pesticide linuron on frogs      (via sciencedaily.com)     Original source 

Grand-offspring of male frogs exposed to the pesticide linuron exhibited changes in their DNA that was linked to significant physiological impacts, a study reveals. The research highlights the profound transgenerational consequences of environmental pollution on amphibian populations, which are already under threat of extinction.

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Published

Researchers uncover protein responsible for cold sensation      (via sciencedaily.com)     Original source 

Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

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Published

Research sheds light on new strategy to treat infertility      (via sciencedaily.com)     Original source 

New research describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos. The technique could be used by women of advanced maternal age or for those who are unable to produce viable eggs due to previous treatment for cancer or other causes. It also raises the possibility of men in same-sex relationships having children who are genetically related to both parents.