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Categories: Biology: Genetics, Mathematics: Puzzles
Published New method traces ancestry of hybrid plants and animals
(via sciencedaily.com) Original source Hybrid plants and animals have complicated genomes. A biologist has discovered a way to reveal their parent species.
Published CRISPR/Cas9-based gene drive could suppress agricultural pests
(via sciencedaily.com) Original source Researchers have now used a gene-drive system to suppress an important agricultural pest.
Published When water temperatures change, the molecular motors of cephalopods do too
(via sciencedaily.com) Original source Working with live squid hatchlings, scientists find the animals can tune their proteome on the fly in response to changes in ocean temperature via the unique process of RNA recoding. The findings inspire new questions about basic protein function.
Published Study unravels the mysteries of actin filament polarity
(via sciencedaily.com) Original source An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles.
Published Octopuses rewire their brains to adapt to seasonal temperature shifts
(via sciencedaily.com) Original source Octopuses don't thermoregulate, so their powerful brains are exposed to -- and potentially threatened by -- changes in temperature. Researchers report that two-spot octopuses adapt to seasonal temperature shifts by producing different neural proteins under warm versus cool conditions. The octopuses achieve this by editing their RNA, the messenger molecule between DNA and proteins. This rewiring likely protects their brains, and the researchers suspect that this unusual strategy is used widely amongst octopuses and squid.
Published Remains of an extinct world of organisms discovered
(via sciencedaily.com) Original source Newly discovered biomarker signatures point to a whole range of previously unknown organisms that dominated complex life on Earth about a billion years ago. They differed from complex eukaryotic life as we know it, such as animals, plants and algae in their cell structure and likely metabolism, which was adapted to a world that had far less oxygen in the atmosphere than today.
Published Older trees accumulate more mutations than their younger counterparts
(via sciencedaily.com) Original source A study of the relationship between the growth rate of tropical trees and the frequency of genetic mutations they accumulate suggests that older, long-lived trees play a greater role in generating and maintaining genetic diversity than short-lived trees.
Published A compound from fruit flies could lead to new antibiotics
(via sciencedaily.com) Original source Research shows that the natural peptide, called drosocin, protects fruit flies from bacterial infections by binding to ribosomes in bacteria. Once bound, drosocin prevents the ribosome from making new proteins.
Published CRISPR/Cas9 reveals a key gene involved in the evolution of coral skeleton formation
(via sciencedaily.com) Original source New work uses cutting-edge CRISPR/Cas9 genome editing tools to reveal a gene that's critical to stony corals' ability to build their reef architectures. This research could inform coral conservation and restoration efforts.
Published Genomes of 233 primate species sequenced
(via sciencedaily.com) Original source Researchers from 24 countries have analyzed the genomes of 809 individuals from 233 primate species, generating the most complete catalog of genomic information about our closest relatives to date. The project provides new insights into the evolution of primates, including humans, and their diversity. In baboons, for example, hybridization and gene flow between different species occurred in the past and is still ongoing in several regions of their range. This makes baboons a good model for the evolution of early human lineages within and outside Africa. In addition, using a specially designed AI algorithm, the genomic data enable new insights into the genetic causes of human diseases.
Published New class of antibiotics to fight resistant bacteria
(via sciencedaily.com) Original source Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.
Published Symbiotic and pathogenic fungi may use similar molecular tools to manipulate plants
(via sciencedaily.com) Original source Symbiotic and pathogenic fungi that interact with plants are distantly related and don't share many genetic similarities. Comparing plant pathogenic fungi and plant symbiotic fungi, scientists at the Sainsbury Laboratory Cambridge University (SLCU) have discovered that these remote relatives are using a similar group of proteins to manipulate and live within plants.
Published DNA damage repaired by antioxidant enzymes
(via sciencedaily.com) Original source In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.
Published Engineers report low-cost human biomarker sensor designs
(via sciencedaily.com) Original source Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.
Published Honey bee colony aggression linked to gene regulatory networks
(via sciencedaily.com) Original source In honey bees, the role a bee plays in the colony changes as they age. Younger bees perform duties inside the hive, such as nursing and wax building, while older bees transition to roles outside of the hive, either foraging for food (foragers) or defending the colony (soldiers). What determines whether older bees become foragers or soldiers is unknown, but a new studyexplores the genetic mechanisms underlying the collective behavior of colony defense, and how these mechanisms relate to the colony's overall aggression.
Published Researchers show mobile elements monkeying around the genome
(via sciencedaily.com) Original source Whole-genomic sequencing has revolutionized the amount and detail of genetic diversity now available to researchers to study. While the researchers previously had looked at a few hundred mobile elements or 'jumping genes,' primarily of the Alu and L1 types, they were now able to analyze over 200,000 elements computationally, confirming and expanding on previous studies. Their findings provide more evidence of the fluidity of species and continuous spread of mobile and transposable genetic elements.
Published A protein mines, sorts rare earths better than humans, paving way for green tech
(via sciencedaily.com) Original source Rare earth elements, like neodymium and dysprosium, are a critical component to almost all modern technologies, from smartphones to hard drives, but they are notoriously hard to separate from the Earth's crust and from one another. Scientists have discovered a new mechanism by which bacteria can select between different rare earth elements, using the ability of a bacterial protein to bind to another unit of itself, or 'dimerize,' when it is bound to certain rare earths, but prefer to remain a single unit, or 'monomer,' when bound to others.
Published Phenomenal phytoplankton: Scientists uncover cellular process behind oxygen production
(via sciencedaily.com) Original source According to new research, the amount of oxygen in one of 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton. The new study identifies how a proton pumping enzyme (known as VHA) aids in global oxygen production and carbon fixation from phytoplankton.
Published Geneticists discover hidden 'whole genome duplication' that may explain why some species survived mass extinctions
(via sciencedaily.com) Original source Geneticists have unearthed a major event in the ancient history of sturgeons and paddlefish that has significant implications for the way we understand evolution. They have pinpointed a previously hidden 'whole genome duplication' (WGD) in the common ancestor of these species, which seemingly opened the door to genetic variations that may have conferred an advantage around the time of a major mass extinction some 200 million years ago.
Published How the flu virus hacks our cells
(via sciencedaily.com) Original source Influenza epidemics, caused by influenza A or B viruses, result in acute respiratory infection. They kill half a million people worldwide every year. These viruses can also wreak havoc on animals, as in the case of avian flu. A team has now identified how the influenza A virus manages to penetrate cells to infect them. By attaching itself to a receptor on the cell surface, it hijacks the iron transport mechanism to start its infection cycle. By blocking the receptor involved, the researchers were also able to significantly reduce its ability to invade cells. These results highlight a vulnerability that could be exploited to combat the virus.