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Categories: Biology: Genetics, Mathematics: Modeling
Published AI model aids early detection of autism



A new machine learning model can predict autism in young children from relatively limited information. The model can facilitate early detection of autism, which is important to provide the right support.
Published Why do researchers often prefer safe over risky projects? Explaining risk aversion in science



A mathematical framework that builds on the economic theory of hidden-action models provides insight into how the unobservable nature of effort and risk shapes investigators' research strategies and the incentive structures within which they work, according to a new study.
Published Probiotics during pregnancy shown to help moms and babies



Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.
Published Zebrafish use surprising strategy to regrow spinal cord



A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics



Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.
Published Revealing the mysteries within microbial genomes



A new technique will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet's diverse microbiomes.
Published How bread dough gave rise to civilization



A major international study has explained how bread wheat helped to transform the ancient world on its path to becoming the iconic crop that today helps sustain a global population of eight billion.
Published Beige fat cells with a 'Sisyphus mechanism'



A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published In subdivided communities cooperative norms evolve more easily



Researchers simulated social norms with a supercomputer. Their findings contribute to a deeper understanding of the evolution of social norms and their role in fostering cooperative behavior.
Published A ketogenic diet could improve the response to pancreatic cancer therapy



Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome



Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Leading AI models struggle to identify genetic conditions from patient-written descriptions



Researchers discover that while artificial intelligence (AI) tools can make accurate diagnoses from textbook-like descriptions of genetic diseases, the tools are significantly less accurate when analyzing summaries written by patients about their own health. These findings demonstrate the need to improve these AI tools before they can be applied in health care settings to help make diagnoses and answer patient questions.
Published Researchers call for genetically diverse models to drive innovation in drug discovery



Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.
Published Exciting advance in stem cell therapy



A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges



A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Rewriting the evolutionary history of critical components of the nervous system



A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published Starvation and adhesion drive formation of keratinocyte patterns in skin



Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.
Published Think fast -- or not: Mathematics behind decision making



New research explains the mathematics behind how initial predispositions and additional information affect decision making.
Published AI poses no existential threat to humanity, new study finds



Large Language Models (LLMs) are entirely controllable through human prompts and lack 'emergent abilities'; that is, the means to form their own insights or conclusions. Increasing model size does not lead LLMs to gain emergent reasoning abilities, meaning they will not develop hazardous abilities and therefore do not pose an existential threat. A new study sheds light on the (until now unexplained) capabilities and shortcomings of LLMs, including the need for carefully engineered prompts to exhibit good performance.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease



Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.