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Categories: Biology: Genetics, Mathematics: Modeling
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper
(via sciencedaily.com) Original source A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published Discovery: Plants use 'Trojan horse' to fight mold invasions
(via sciencedaily.com) Original source Scientists have discovered that plants send tiny, innocuous-seeming lipid 'bubbles' filled with RNA across enemy lines, into the cells of the aggressive mold. Once inside, different types of RNA come out to suppress the infectious cells that sucked them in.
Published Using AI, researchers identify a new class of antibiotic candidates
(via sciencedaily.com) Original source Using artificial intelligence, researchers discovered a class of compounds that can kill methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant bacterium that causes more than 10,000 deaths in the U.S. each year.
Published A trillion scents, one nose
(via sciencedaily.com) Original source A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities
(via sciencedaily.com) Original source The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published The evolutionary timeline of diminished boric acid and urea transportation in aquaporin 10
(via sciencedaily.com) Original source Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells. However, Aqp10.2b in pufferfishes allows only the passage of water and glycerol and not urea and boric acid. Researchers sought to understand the evolutionary timeline that resulted in the variable substrate selection mechanisms among Aqp10s. Their results indicate that Aqp10.2 in ray-finned fishes may have reduced or lost urea and boric acid permeabilities through evolution.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells
(via sciencedaily.com) Original source Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published Large language models validate misinformation
(via sciencedaily.com) Original source In a recent study, researchers systematically tested an early version of ChatGPT's understanding of statements in six categories: facts, conspiracies, controversies, misconceptions, stereotypes, and fiction.
Published Protein allows poison dart frogs to accumulate toxins safely
(via sciencedaily.com) Original source A newly identified protein helps poison dart frogs accumulate and store a potent toxin in their skin which they use for self-defence against predators.
Published Genetic diversity of wild north American grapes mapped
(via sciencedaily.com) Original source Wild North American grapes are now less of a mystery after researchers decoded and catalogued the genetic diversity of nine species of this valuable wine crop.
Published Genetics of host plants determine what microorganisms they attract
(via sciencedaily.com) Original source Plants often develop communities with microorganisms in their roots, which influences plant health and development. Although the recruitment of these microbes is dictated by several factors, it is unclear whether the genetic variation in the host plants plays a role.
Published Clinicians could be fooled by biased AI, despite explanations
(via sciencedaily.com) Original source A new study finds that clinicians were fooled by biased AI models, even with provided explanations for how the model generated its diagnosis.
Published AI's memory-forming mechanism found to be strikingly similar to that of the brain
(via sciencedaily.com) Original source An interdisciplinary team consisting of researchers has revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain. This new finding provides a novel perspective on memory consolidation, which is a process that transforms short-term memories into long-term ones, in AI systems.
Published Algae as a surprising meat alternative and source of environmentally friendly protein
(via sciencedaily.com) Original source A new study has demonstrate that the ingestion of two of the most commercially available algal species are rich in protein which supports muscle remodeling in young healthy adults. Their findings suggest that algae may be an interesting and sustainable alternative to animal-derived protein with respect to maintaining and building muscle.
Published Artificial intelligence can predict events in people's lives
(via sciencedaily.com) Original source Artificial intelligence can analyze registry data on people's residence, education, income, health and working conditions and, with high accuracy, predict life events.
Published Genetic atlas detailing early stages of zebrafish development
(via sciencedaily.com) Original source Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.
Published Acid sensor and calcium store discovered in plants
(via sciencedaily.com) Original source Using optogenetics, researchers have detected a new acid sensor in plant cells that is addressing a cell-internal calcium store.
Published Computational model captures the elusive transition states of chemical reactions
(via sciencedaily.com) Original source Researchers developed a way to quickly calculate the transition state structure of a chemical reaction, using machine-learning models.
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published New understanding of ancient genetic parasite may spur medical breakthroughs
(via sciencedaily.com) Original source Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.