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Categories: Biology: Genetics, Mathematics: Modeling
Published Board games are boosting math ability in young children
(via sciencedaily.com) Board games based on numbers, like Monopoly, Othello and Chutes and Ladders, make young children better at math, according to a comprehensive review of research published on the topic over the last 23 years.
Published Machine learning takes materials modeling into new era
(via sciencedaily.com) The arrangement of electrons in matter, known as the electronic structure, plays a crucial role in fundamental but also applied research such as drug design and energy storage. However, the lack of a simulation technique that offers both high fidelity and scalability across different time and length scales has long been a roadblock for the progress of these technologies. Researchers have now pioneered a machine learning-based simulation method that supersedes traditional electronic structure simulation techniques. Their Materials Learning Algorithms (MALA) software stack enables access to previously unattainable length scales.
Published Deciphering the thermodynamic arrow of time in large-scale complex networks
(via sciencedaily.com) A solution for temporal asymmetry -- or entropy production -- in thermodynamics has been developed to further our understanding of the behavior of biological systems, machine learning, and AI tools. The researchers worked on the time-irreversible Ising model dynamics caused by asymmetric connections between neurons.
Published Researchers teach an AI to write better chart captions
(via sciencedaily.com) Original source A new tool helps scientists develop machine-learning models that generate richer, more detailed captions for charts, and vary the level of complexity of a caption based on the needs of users. This could help improve accessibility for people with visual disabilities.
Published Evaluating cybersecurity methods
(via sciencedaily.com) Original source Researchers created a generic framework that enables an engineer or scientist to evaluate the effectiveness of defense schemes that seek to limit a hacker's ability to learn secret information by observing the behavior of a victim computer program.
Published Turning old maps into 3D digital models of lost neighborhoods
(via sciencedaily.com) Original source Imagine strapping on a virtual reality headset and 'walking' through a long-gone neighborhood in your city -- seeing the streets and buildings as they appeared decades ago. That's a very real possibility now that researchers have developed a method to create 3D digital models of historic neighborhoods using machine learning and historic Sanborn Fire Insurance maps.
Published Genetic secrets of America's favorite snack
(via sciencedaily.com) Original source In its simplest form, popcorn is pretty uncomplicated. Most supermarket varieties offer the choice of two kernel colors, yellow or white, and two kernel shapes, pointed or pearl. When popped, the flake typically expands into one of two shapes: mushroom or butterfly. But there's more to popcorn than meets the eye. New research reveals a wealth of untapped diversity lurking in popcorn's genetic code.
Published Researchers develop digital test to directly measure HIV viral load
(via sciencedaily.com) Original source A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies. Called the viral load, this is what is measured to allow clinicians to understand how patients are responding to anti-viral medications and monitor potential progression. The time-consuming viral load testing needs to be repeated several times as a patient undergoes treatment. Now, a research team has developed a time and cost-efficient digital assay that can directly measure the presence of HIV in single drop of blood.
Published How coral reefs can survive climate change
(via sciencedaily.com) Original source Similar to the expeditions of a hundred or two hundred years ago, the Tara Pacific expedition lasted over two years. The goal: to research the conditions for life and survival of corals. The ship crossed the entire Pacific Ocean, assembling the largest genetic inventory conducted in any marine system to date. The team's 70 scientists from eight countries took around 58,000 samples from the hundred coral reefs studied.
Published Extinct warbler's genome sequenced from museum specimens
(via sciencedaily.com) Original source The Bachman's warbler, a songbird that was last seen in North America nearly 40 years ago, was a distinct species and not a hybrid of its two living sister species, according a new study in which the full genomes of seven museum specimens of the bird were sequenced.
Published Drug decelerates bacterial race to antibiotic resistance
(via sciencedaily.com) Original source Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.
Published Researcher uses pressure to understand RNA dynamics
(via sciencedaily.com) Original source Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
Published The molecular control center of our protein factories
(via sciencedaily.com) Original source Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
Published The clue is in the glue -- Nature's secret for holding it together
(via sciencedaily.com) Original source An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.
Published Generative AI models are encoding biases and negative stereotypes in their users
(via sciencedaily.com) Original source In the space of a few months generative AI models, such as ChatGPT, Google's Bard and Midjourney, have been adopted by more and more people in a variety of professional and personal ways. But growing research is underlining that they are encoding biases and negative stereotypes in their users, as well as mass generating and spreading seemingly accurate but nonsensical information. Worryingly, marginalized groups are disproportionately affected by the fabrication of this nonsensical information.
Published A roadmap for gene regulation in plants
(via sciencedaily.com) Original source For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.
Published Now, every biologist can use machine learning
(via sciencedaily.com) Original source Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.
Published DNA can fold into complex shapes to execute new functions
(via sciencedaily.com) Original source DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.
Published Plant extracts used by indigenous people hold promise in treatment of ataxia
(via sciencedaily.com) Original source Researchers have discovered that extracts from plants used by the Kwakwaka'wakw First Nations peoples in their traditional botanical medicine practices are able to rescue the function of ion channel proteins carrying mutations that cause human Episodic Ataxia.
Published Researchers reveal mechanism of protection against breast and ovarian cancer
(via sciencedaily.com) Original source Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.