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Categories: Biology: Genetics, Mathematics: Modeling
Published Eat right, live longer: Could a moderate protein diet be the coveted elixir of youth?
(via sciencedaily.com) Original source Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers fed isocaloric diets with varying amounts of protein to young and middle-aged male mice. They found that the mice were metabolically healthier when fed moderate-protein diets. These findings could provide valuable insights into developing nutritional interventions and improving metabolic health in people.
Published Light conveyed by the signal transmitting molecule sucrose controls growth of plant roots
(via sciencedaily.com) Original source Researchers shows how information about the quantity of absorbed light passes from the leaves to the roots. Photosynthetic sucrose not only supplies roots with carbohydrates but also acts as a signal transmitter for light-dependent root architecture.
Published Scientists unveil RNA-guided mechanisms driving cell fate
(via sciencedaily.com) Original source The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published Evolution driving improvements in racehorse speed
(via sciencedaily.com) Original source A new study has found that genetic improvement is underlying the increasing speed of Britain's thoroughbreds. This contrasts with earlier studies that suggested racehorses were showing no genetic improvement in response to selection by breeders.
Published Groundbreaking images of root chemicals offer new insights on plant growth
(via sciencedaily.com) Original source Applying imaging technology to plant roots, researchers have developed a new understanding of chemicals that are responsible for plant growth. The chemical 'roadmap' identifies where key molecules are distributed along corn roots and how their placement factors into the plant's maturation.
Published Protein-based nano-'computer' evolves in ability to influence cell behavior
(via sciencedaily.com) Original source The first protein-based nano-computing agent that functions as a circuit has been created. The milestone puts them one step closer to developing next-generation cell-based therapies to treat diseases like diabetes and cancer.
Published Using AI, scientists find a drug that could combat drug-resistant infections
(via sciencedaily.com) Original source Using AI, researchers identified a new antibiotic that can kill Acinetobacter baumannii, a type of bacteria that is responsible for many drug-resistant infections.
Published How sweet it is: The fruit fly gut influences reproduction by 'tasting' fructose
(via sciencedaily.com) Original source A research group has found that in fruit flies (Drosophila melanogaster), circulating fructose derived from dietary sugar is needed for enhanced egg production after mating. In this species, circulating fructose is required for an increase in germline stem cells, which divide into reproductive cells. This increase leads to enhanced post-mating egg production. These findings may help to determine whether fructose influences the reproduction of mammals, including humans.
Published Researchers successfully induce primate oocytes in the lab
(via sciencedaily.com) Original source The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published Scientists propose revolution in complex systems modelling with quantum technologies
(via sciencedaily.com) Original source Scientists have made a significant advancement with quantum technologies that could transform complex systems modelling with an accurate and effective approach that requires significantly re-duced memory.
Published How tasty is the food?
(via sciencedaily.com) Original source A hormone and specialized brain cells regulate feeding behavior in mice.
Published New method predicts extreme events more accurately
(via sciencedaily.com) Original source A new study has used global storm-resolving simulations and machine learning to create an algorithm that can deal separately with two different scales of cloud organization: those resolved by a climate model, and those that cannot be resolved as they are too small. This new approach addresses the missing piece of information in traditional climate model parameterizations and provides a way to predict precipitation intensity and variability more precisely.
Published Where do our limbs come from?
(via sciencedaily.com) Original source Scientists have uncovered new clues about the origin of paired appendages -- a major evolutionary step that remains unresolved and highly debated.
Published A look into the heart of cellular waste disposal
(via sciencedaily.com) Original source Researchers reveal how a nanomachine takes care of cleaning up inside the cell.
Published Engineers create bacteria that can synthesize an unnatural amino acid
(via sciencedaily.com) Original source Researchers have engineered bacteria to synthesize an amino acid that contains a rare functional group that others have shown to have implications in the regulation of our immune system. The researchers also taught a single bacterial strain to create the amino acid and place it at specific sites within target proteins. These findings provide a foundation for developing unique vaccines and immunotherapies in the future.
Published Researchers find new mechanism for sodium salt detoxification in plants
(via sciencedaily.com) Original source A team of researchers has found a mechanism in thale cress (Arabidopsis thaliana) which enables plants to provide protection against salt stress for their sensitive stem cells in the meristem at the root tip.
Published Study may explain why high-sugar diets can worsen IBD
(via sciencedaily.com) Original source Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study that could help get to the bottom of why limiting sugary foods can ease symptoms for patients with IBD.
Published A multiomics approach provides insights into flu severity
(via sciencedaily.com) Original source Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.
Published Designing synthetic receptors for precise cell control
(via sciencedaily.com) Original source Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications.
Published Under control to the very end -- how our cells kill themselves
(via sciencedaily.com) Original source Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers have now been able to elucidate the exact mechanism at the atomic level.