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Categories: Biology: Genetics, Ecology: Research
Published E. coli variant may cause antimicrobial resistance in dogs, humans
(via sciencedaily.com) Original source Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
Published Researchers find that frogs can quickly increase their tolerance to pesticides
(via sciencedaily.com) Original source Although there is a large body of research on pests evolving tolerances for the pesticides meant to destroy them, there have been considerably fewer studies on how non-target animals in these ecosystems may do the same.
Published Unlocking the mystery of preexisting drug resistance: New study sheds light on cancer evolution
(via sciencedaily.com) Original source The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence of treatment due to a reduced growth rate, preexisting resistance is pervasive across diseases that evolve -- like cancer and pathogens -- defying conventional wisdom.
Published History shows that humans are good for biodiversity... sometimes
(via sciencedaily.com) Original source Humans have been an important driver of vegetation change over thousands of years, and, in some places, had positive impacts on biodiversity, according to a new study.
Published Loss of oxygen in lakes and oceans a major threat to ecosystems, society, and planet
(via sciencedaily.com) Original source Oxygen is a fundamental requirement of life, and the loss of oxygen in water, referred to as aquatic deoxygenation, is a threat to life at all levels. In fact, researchers describe how ongoing deoxygenation presents a major threat to the stability of the planet as a whole.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer
(via sciencedaily.com) Original source Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle
(via sciencedaily.com) Original source A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.
Published Study examines urban forests across the United States
(via sciencedaily.com) Original source Tree-planting campaigns have been underway in the United States, especially in cities, as part of climate mitigation efforts given the many environmental benefits of urban forests. But a new study finds that some areas within urban forests in the U.S., may be more capable than trees growing around city home lawns in adapting to a warmer climate.
Published A better way to make RNA drugs
(via sciencedaily.com) Original source RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Insight into one of life's earliest ancestors revealed in new study
(via sciencedaily.com) Original source Researchers have shed light on Earth's earliest ecosystem, showing that within a few hundred million years of planetary formation, life on Earth was already flourishing.
Published How plant cold specialists can adapt to the environment
(via sciencedaily.com) Original source Evolutionary biologists studied spoonworts to determine what influence genome duplication has on the adaptive potential of plants. The results show that polyploids -- species with more than two sets of chromosomes -- can have an accumulation of structural mutations with signals for a possible local adaptation, enabling them to occupy ecological niches time and time again.
Published Mapping the world's fungi from air samples
(via sciencedaily.com) Original source Researchers have found that the key to a quick and cost-effective mapping of biodiversity has been right in front of our eyes all along, but at the same time invisible -- i.e., in the air that surrounds us.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed
(via sciencedaily.com) Original source International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin
(via sciencedaily.com) Original source An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness
(via sciencedaily.com) Original source Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published Pumpkin disease not evolving, could make a difference for management
(via sciencedaily.com) Original source The pathogen that causes bacterial spot is very good at what it does. Forming small lesions on the rinds of pumpkins, melons, cucumbers, and other cucurbits, it mars the fruits' appearance and ushers in secondary pathogens that lead to rot and severe yield loss. The bacterium, Xanthomonas cucurbitae, is so successful that it has had no reason to evolve through time or space.
Published Atlas of proteins reveals inner workings of cells
(via sciencedaily.com) Original source Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Not so simple: Mosses and ferns offer new hope for crop protection
(via sciencedaily.com) Original source Mosses, liverworts, ferns and algae may offer an exciting new research frontier in the global challenge of protecting crops from the threat of disease.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease
(via sciencedaily.com) Original source Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published Big gain in battle against harmful bacteria
(via sciencedaily.com) Original source An unexpected find has enabled important progress to be made in the battle against harmful bacteria.