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Categories: Biology: Genetics, Ecology: Research
Published Researchers investigate how freshwater diatoms stay in the light



Researchers sought to understand how diatoms -- microscopic, photosynthetic algae that make up an estimated 20 percent of global carbon sequestration and oxygen production -- are able to bloom in an ice-covered Lake Erie and how ice decline across the Great Lakes is impacting the algae.
Published Decoding the Easter Bunny -- an eastern Finnish brown hare to represent the standard for the species' genome



Biologists have published a chromosomally assembled reference genome for the European brown hare. The genome consists of 2.9 billion base pairs, which form 23 autosomal chromosomes, and X and Y sex chromosomes. The timing of the genome release is very appropriate as the brown hare also represents the original Easter Bunny familiar from European folklore.
Published Across oceans and millennia: decoding the origin and history of the bottle gourd



Researchers have uncovered intriguing details about the origins and spread of the bottle gourd, one of the oldest domesticated crops. Their work unveils the genetic diversification and population history of this hard-shelled plant that was used to make bottles, instruments, and containers for over 10,000 years by ancient civilizations.
Published Fiber, genes and the gut microbiome: Study reveals possible triggers for inflammatory bowel disease



A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
Published Empty 'backpacks' activate the immune system against cancer



Researchers have discovered that the mere act of attaching their microparticle 'backpacks' to neutrophils is enough to activate them against cancer -- no drugs needed. In experiments, backpack-bearing neutrophils shrank tumors and extended the survival of mice with cancer, and treated animals retained an immune memory of the disease. This approach opens the door to a new class of drug-free immunotherapy for cancer.
Published A protein found in human sweat may protect against Lyme disease



Human sweat contains a protein that may protect against Lyme disease. About one-third of the population carries a genetic variant of this protein that is associated with Lyme disease in genome-wide association studies.
Published Genes identified that allow bacteria to thrive despite toxic heavy metal in soil



Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found. This enables the bacteria to not only thrive in otherwise toxic soils but help plants grow there as well. A research team pinpointed a set of genes in wild soil bacteria that allows them to do this in serpentine soils which have naturally high concentrations of toxic nickel. The genetic discovery could help inform future bioremediation efforts that seek to return plants to polluted soils.
Published Artificial streams reveal how drought shapes California's alpine ecosystems



Researchers have used a series of artificial stream channels to mimic the behavior of headwater creeks under future climate change scenarios. They found that drier conditions shifted the life cycles of the algae and insects that form the base of the alpine food web. However, because species adjusted to the shifts in a variety of ways, the stream ecosystems were generally resilient to the changing conditions.
Published Engineers measure pH in cell condensates



In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Why do tree frogs lay their eggs on the ground?



A curious aspect of tree frogs is that they often lay their eggs on the ground where the risk of predation by natural enemies is greater than in the trees where they live. A research team suggested that the reason for this behavior is to protect the eggs from low temperatures. Their findings highlight the challenge faced by tree frogs: Should they attempt to maintain an optimal temperature for their eggs or risk predation?
Published Arctic nightlife: Seabird colony bursts with sound at night



Acoustic recordings of a colony of little auks reveal their nocturnal activities and offer valuable monitoring means for avian biology in the Arctic.
Published Machine learning classifier accelerates the development of cellular immunotherapies



Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published Protein fragments ID two new 'extremophile' microbes--and may help find alien life



Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.
Published It's hearty, it's meaty, it's mold



Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.
Published New bioengineered protein design shows promise in fighting COVID-19



A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published New discovery reveals how the egg controls sperm entry



After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Even cells know the importance of recycling



Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published Sulfur and the origin of life



A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published Tryptophan in diet, gut bacteria protect against E. coli infection



Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published Marine heat waves disrupt the ocean food web in the northeast Pacific Ocean



Marine heat waves in the northeast Pacific Ocean create ongoing and complex disruptions of the ocean food web that may benefit some species but threaten the future of many others, a new study has shown.