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Categories: Biology: Genetics, Ecology: Extinction
Published The reasons why insect numbers are decreasing



Researchers are investigating the causes and consequences of the worldwide insect decline as well as considering potential countermeasures.
Published Scientists slow aging by engineering longevity in cells



Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Genomes from 240 mammal species explain human disease risks



Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease? A major international research project has surveyed and analyzed the genomes of 240 different mammals. The results show how the genomes of humans and other mammals have developed over the course of evolution. The research shows which regions have important functions in mammals, which genetic changes have led to specific characteristics in different species and which mutations can cause disease.
Published One famous dog and a powerful new approach for understanding biology and evolutionary history



Ever since scientists first read the complete genetic codes of creatures like fruit flies and humans more than two decades ago, the field of genomics has promised major leaps forward in understanding basic questions in biology. Two recent articles break new ground by showing how much valuable information can be found in genomes of a single species, such as endangered orcas, or even in the DNA of an individual. That individual is a sled dog named Balto, who has been immortalized in movies and a statue for helping to bring lifesaving diphtheria antitoxin to Nome, Alaska in an epic journey across the Alaskan wilderness in the winter of 1925. With just a snippet of the dog's preserved skin researchers have made great discoveries.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting



CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human



What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease



Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published How dormant bacteria come back to life



Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Ant mounds are more important for biodiversity than previously thought



The ant mounds on the heath, in the forest and in your garden are oases for life. The heat and nutrients from ant mounds make them the perfect home for unique plant and animal species, according to new research.
Published Researchers explore techniques to successfully reintroduce captive birds into the wild



Studies show that some species may require breeding in captivity within the next 200 years to avoid extinction. This reality places heavy importance on the reintroduction practices used to successfully transfer species from captivity to the wild. A new study looks at some of the most popular conservation techniques and identifies which have the highest likelihood of success for the reintroduction of bird species back into the wild.
Published Twilight zone at risk from climate change



Life in the ocean's 'twilight zone' could decline dramatically due to climate change, new research suggests.
Published New findings indicate gene-edited rice might survive in Martian soil



New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published Prehistoric scat reveals 'Waves' of extinction in Colombia



Fungal spores found in dung have revealed that large animals went extinct in two 'waves' in the Colombian Andes.
Published Near-universal T cell immunity towards a broad range of bacteria



Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Luring the virus into a trap



Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair



The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Neuroptera: Greater insect diversity in the Cretaceous period



An LMU team has studied the biodiversity of larvae from the insect order neuroptera over the past 100 million years.
Published Researchers reveal a map to study novel form of cell-to-cell communication



An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Cheetahs need more space: Reintroduction in India must consider their spatial ecology



In autumn 2022 and winter 2023, a total of 20 cheetahs from Namibia and South Africa were introduced to Kuno National Park in India to establish a free-ranging population -- for the first time since their extinction in India 70 years ago. Although the idea may be commendable, getting it right is not so easy. Scientists see shortcomings in the reintroduction plan: In southern Africa, cheetahs live in a stable socio-spatial system with widely spread territories and densities of less than one individual per 100 km².
Published Reinforcement learning: From board games to protein design



An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.