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Categories: Biology: Genetics, Ecology: Extinction
Published Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat
(via sciencedaily.com) Original source Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat. Scientists have traced the family trees of two transmissible cancers that affect Tasmanian devils and have pinpointed mutations which may drive growth of deadly diseases.
Published The climate crisis and biodiversity crisis can't be approached as two separate things
(via sciencedaily.com) Original source Anthropogenic climate change has, together with the intensive use and destruction of natural ecosystems through agriculture, fishing and industry, sparked an unprecedented loss of biodiversity that continues to worsen. In this regard, the climate crisis and biodiversity crisis are often viewed as two separate catastrophes. An international team of researchers calls for adopting a new perspective.
Published Fungal genetics could help develop novel biotechnologies
(via sciencedaily.com) Original source An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.
Published AI system can generate novel proteins that meet structural design targets
(via sciencedaily.com) Original source A new machine-learning system can generate protein designs with certain structural features, and which do not exist in nature. These proteins could be utilized to make materials that have similar mechanical properties to existing materials, like polymers, but which would have a much smaller carbon footprint.
Published Engineering the next generation of cell and gene therapies
(via sciencedaily.com) Original source Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.
Published African penguins: Climate refugees from a distant past?
(via sciencedaily.com) Original source Imagine the view from the western coastline of southern Africa during the Last Glacial Maximum (LGM) over twenty thousand years ago: in the distance you would see at least fifteen large islands -- the largest 300 square kilometers in area -- swarming with hundreds of millions of marine birds and penguin colonies.
Published Simple addition to corn bran could boost grain's nutritional value 15-35%
(via sciencedaily.com) Original source What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.
Published Study links 'stuck' stem cells to hair turning gray
(via sciencedaily.com) Original source Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.
Published Loops, flags and tension in DNA
(via sciencedaily.com) Original source Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.
Published New mechanism for DNA folding
(via sciencedaily.com) Original source A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.
Published Novel nanocages for delivery of small interfering RNAs
(via sciencedaily.com) Original source Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.
Published The diversity of present tree species is shaped by climate change in the last 21,000 years
(via sciencedaily.com) Original source A new global survey of 1000 forest areas shows how climate change since the peak of the last ice age has had a major impact on the diversity and distribution of tree species we see today. The results can help us predict how ecosystems will react to future changes, thus having an impact on conservation management around the globe.
Published SpyLigation uses light to switch on proteins
(via sciencedaily.com) Original source Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.
Published Swimming secrets of prehistoric reptiles unlocked by new study
(via sciencedaily.com) Original source The diverse swimming techniques of the ancient reptiles that ruled the Mesozoic seas have been revealed.
Published New genetic target for male contraception identified
(via sciencedaily.com) Original source Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.
Published Molecular 'Superpower' of antibiotic-resistant bacteria
(via sciencedaily.com) Original source A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study now shows how two molecular mechanisms can work together make the bacterium extra resistant.
Published Learning about what happens to ecology, evolution, and biodiversity in times of mass extinction
(via sciencedaily.com) Original source Studying mass extinction events from the past can build our understanding of how ecosystems and the communities of organisms within them respond. Researchers are looking to the Late Devonian mass extinction which happened around 370 million years ago to better understand how communities of organisms respond in times of great upheaval.
Published Software to untangle genetic factors linked to shared characteristics among different species
(via sciencedaily.com) Original source Scientists have developed a software package to help answer key questions about genetic factors associated with shared characteristics among different species.
Published How a virus causes chromosomal breakage, leading to cancer
(via sciencedaily.com) Original source Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it.
Published Where did the first sugars come from?
(via sciencedaily.com) Original source Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth