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Categories: Biology: Genetics, Ecology: Extinction

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Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.

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In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

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An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.

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Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.

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What can be done when one threatened animal kills another? Scientists studying critically endangered lemurs in Madagascar confronted this difficult reality when they witnessed attacks on lemurs by another vulnerable species, a carnivore called a fosa.

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Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.

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Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.

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The 2010 Gulf of Mexico Deepwater Horizon oil spill, the largest accidental spill in history, released almost 100 million gallons of oil, causing significant pollution. A decade later, its long-term effects remain unclear. A study investigating the impact on endemic fish species found 29 of 78 species unreported in museum collections since the spill, suggesting potential loss of biodiversity.

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Animal and plant populations have been extensively studied, which has helped to understand ecosystem processes and evolutionary adaptations. However, this has not been the case with microbial populations due to the impossibility of isolating, culturing and analyzing the genetic content of the different species and their individuals in the laboratory. Therefore, although it is known that populations of microorganisms include a great diversity, this remains largely uncharacterized.

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The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.

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The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.

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The fossilized remains of a second gigantic jawbone measuring more than two meters long has been found on a beach in Somerset, UK.

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Trying to hit a target size before dividing seems like the best strategy for maintaining a precise cell size, but bacteria don't do that. Now we know why.

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Marine communities migrated to Antarctica during the Earth's warmest period in 66 million years long before a mass-extinction event.

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Using a pair of sensors made from carbon nanotubes, researchers discovered signals that help plants respond to stresses such as heat, light, or attack from insects or bacteria. Farmers could use these sensors to monitor threats to their crops, allowing them to intervene before the crops are lost.

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Researchers who captured footage of dog attacks on endangered mountain tapirs in Colombia are calling for action to protect threatened wildlife.

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Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.

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To make weeding easier, scientists suggest bioengineering crops to be colorful or to have differently shaped leaves so that they can be more easily distinguished from their wild and weedy counterparts. This could involve altering the crops' genomes so that they express pigments that are already produced by many plants, for example, anthocyanins, which make blueberries blue, or carotenoids, which make carrots orange. Then, they say, weeding robots could be trained to remove only the weeds using machine learning.

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Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

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Researchers have shown that an Amazonian butterfly is a hybrid species, formed by two other species breeding together almost 200,000 years ago. Researchers have shown that an Amazonian butterfly is a hybrid species, formed by two other species breeding together almost 200,000 years ago.