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Categories: Biology: Genetics, Ecology: Extinction
Published How did the bushpig cross the strait? A great puzzle in African mammal biogeography solved by genomics



Africa has a huge diversity of large mammals, but their evolutionary relationships and movement across the continent over time often remain a mystery. A new scientific study sheds light on longstanding questions about the interplay between evolution and geography in one of these mammals, namely the iconic African bushpig, and helps settle a major question regarding prehistoric human activities shaping biodiversity patterns in Africa.
Published Researchers discover molecular 'barcode' used by bacteria to secrete toxins



Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
Published Widespread population collapse of African Raptors



An international team of researchers has found that Africa's birds of prey are facing an extinction crisis. The report warns of declines among nearly 90% of 42 species examined, and suggests that more than two-thirds may qualify as globally threatened.
Published Important membrane transport mechanism in pathogenic bacteria



Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.
Published Evolution is not as random as previously thought



A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical accidents.
Published Feathers from deceased birds help scientists understand new threat to avian populations



Animal ecologists developed an analytical approach to better understand one of the latest threats to feathered creatures: the rise of wind and solar energy facilities.
Published The snail or the egg?



Animals reproduce in one of two distinct ways: egg-laying or live birth. By studying an evolutionarily recent transition from egg-laying to live-bearing in a marine snail, collaborative research has shed new light on the genetic changes that allow organisms to make the switch.
Published Scientists engineer plant microbiome to protect crops against disease



Scientists have engineered the microbiome of plants for the first time, boosting the prevalence of 'good' bacteria that protect the plant from disease. The findings could substantially reduce the need for environmentally destructive pesticides.
Published New roles for autophagy genes in cellular waste management and aging



Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins -- and ultimately affect aging.
Published The surprisingly resourceful ways bacteria thrive in the human gut



New research shows that some groups of bacteria in the gut are amazingly resourceful, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well.
Published Nematode proteins shed light on infertility



Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.
Published Study reveals clues to how Eastern equine encephalitis virus invades brain cells



Researchers have determined how Eastern equine encephalitis virus attaches to a receptor it uses to enter and infect cells. The findings laid the groundwork for a receptor decoy molecule that protects mice from encephalitis caused by the virus.
Published Bacteria load their syringes



Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent. A technique that tracks the individual movement of proteins revealed how bacteria accomplish this challenging task.
Published New reasons eating less fat should be one of your resolutions



A new study to motivate your New Year's resolutions: it demonstrates that high-fat diets negatively impact genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system and brain function.
Published Elusive cytonemes guide neural development, provide signaling 'express route'



Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.
Published Big impacts from small changes in cell



Tiny things matter -- for instance, one amino acid can completely alter the architecture of the cell. Researchers have now investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions -- from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed 'isoforms', which are known as gamma actin and beta actin.
Published How jellyfish regenerate functional tentacles in days



At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now.
Published How technology and economics can help save endangered species



A lot has changed in the world since the Endangered Species Act (ESA) was enacted 50 years ago in December 1973. Experts are now discuss how the ESA has evolved and what its future might hold.
Published Researchers map how measles virus spreads in human brain



Researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease. New cases of this disease, which is a complication of the measles virus, may occur as measles reemerges among the unvaccinated, say researchers.
Published GPCR structure: Research reveals molecular origins of function for a key drug target



Scientists reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands.