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Categories: Biology: Genetics, Space: Cosmology
Published Influenza viruses can use two ways to infect cells
(via sciencedaily.com) Original source Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells. This ability helps the viruses infect different species -- and potentially jump between animals and humans.
Published A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
(via sciencedaily.com) Original source CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Published Sun-like stars found orbiting hidden companions
(via sciencedaily.com) Original source Astronomers have uncovered what appear to be 21 neutron stars in orbit around stars like our Sun. The discovery is surprising because it is not clear how a star that exploded winds up next to a star like our Sun.
Published Unique characteristics of previously unexplored protein discovered
(via sciencedaily.com) Original source Research achieves scientific breakthrough in understanding cell division.
Published Immune system in the spotlight
(via sciencedaily.com) Original source Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.
Published Ancient microbes offer clues to how complex life evolved
(via sciencedaily.com) Original source Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.
Published E. coli variant may cause antimicrobial resistance in dogs, humans
(via sciencedaily.com) Original source Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
Published JWST unveils stunning ejecta and CO structures in Cassiopeia A's young supernova
(via sciencedaily.com) Original source Researchers announced the latest findings from the James Webb Space Telescope (JWST) of the supernova remnant, Cassiopeia A (Cas A). These observations of the youngest known core collapse supernova in the Milky Way provide insights into the conditions that lead to the formation and destruction of molecules and dust within supernova ejecta. The study's findings change our understanding of dust formation in the early universe in the galaxies detected by JWST 300 million years after the Big Bang.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer
(via sciencedaily.com) Original source Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Cosmic wrestling match
(via sciencedaily.com) Original source Our universe is around 13.8 billion years old. Over the vastness of this time, the tiniest of initial asymmetries have grown into the large-scale structures we can see through our telescopes in the night sky: galaxies like our own Milky Way, clusters of galaxies, and even larger aggregations of matter or filaments of gas and dust. How quickly this growth takes place depends, at least in today's universe, on a sort of wrestling match between natural forces: Can dark matter, which holds everything together through its gravity and attracts additional matter, hold its own against dark energy, which pushes the universe ever further apart?
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle
(via sciencedaily.com) Original source A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.
Published Vivid portrait of interacting galaxies marks Webb's second anniversary
(via sciencedaily.com) Original source Two for two! A duo of interacting galaxies commemorates the second science anniversary of NASA's James Webb Space Telescope, which takes constant observations, including images and highly detailed data known as spectra. Its operations have led to a 'parade' of discoveries by astronomers around the world.
Published A better way to make RNA drugs
(via sciencedaily.com) Original source RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Insight into one of life's earliest ancestors revealed in new study
(via sciencedaily.com) Original source Researchers have shed light on Earth's earliest ecosystem, showing that within a few hundred million years of planetary formation, life on Earth was already flourishing.
Published How plant cold specialists can adapt to the environment
(via sciencedaily.com) Original source Evolutionary biologists studied spoonworts to determine what influence genome duplication has on the adaptive potential of plants. The results show that polyploids -- species with more than two sets of chromosomes -- can have an accumulation of structural mutations with signals for a possible local adaptation, enabling them to occupy ecological niches time and time again.
Published How the 'heart and lungs' of a galaxy extend its life
(via sciencedaily.com) Original source Galaxies avoid an early death because they have a 'heart and lungs' which effectively regulate their 'breathing' and prevent them growing out of control, a new study suggests. If they didn't, the universe would have aged much faster than it has and all we would see today is huge 'zombie' galaxies teeming with dead and dying stars. That's according to a new study that investigates one of the great mysteries of the Universe -- why galaxies are not as large as astronomers would expect.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed
(via sciencedaily.com) Original source International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin
(via sciencedaily.com) Original source An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness
(via sciencedaily.com) Original source Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published Pumpkin disease not evolving, could make a difference for management
(via sciencedaily.com) Original source The pathogen that causes bacterial spot is very good at what it does. Forming small lesions on the rinds of pumpkins, melons, cucumbers, and other cucurbits, it mars the fruits' appearance and ushers in secondary pathogens that lead to rot and severe yield loss. The bacterium, Xanthomonas cucurbitae, is so successful that it has had no reason to evolve through time or space.