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Categories: Biology: Genetics, Space: Cosmology

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Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.

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A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.

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Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.

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Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.

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Sunflowers famously turn their faces to follow the sun as it crosses the sky. But how do sunflowers 'see' the sun to follow it? Plant biologists show that they use a different, novel mechanism from that previously thought.

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Giant gas planets can be agents of chaos, ensuring nothing lives on their Earth-like neighbors around other stars. New studies show, in some planetary systems, the giants tend to kick smaller planets out of orbit and wreak havoc on their climates.

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Researchers introduce the 'Telomouse'. By making a subtle genetic alteration in standard lab mice, they've made the mouse telomeres, which protect the chromosome ends, more closely resemble those in humans. The Telomouse model, developed by incorporating a genetic variation from a mouse species with naturally shorter telomeres, provides a valuable resource for in-depth aging and cancer research. This discovery promises to reveal new insights into the genetics of aging and may contribute to enhanced longevity and well-being.

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There are high hopes for hydrogen as the key to the energy transition. A specific enzyme group found in algae and in bacteria can produce molecular hydrogen simply by catalyzing protons and electrons. However, the enzyme group is so sensitive to oxygen that commercial use of the hydrogen produced by this process as a green energy source is not yet possible. Researchers have now increased the oxygen stability of a hydrogen-producing enzyme by genetically generated channel blockages.

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Cat hair could be the purr-fect way to catch criminals, according to researchers.

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Dendritic cells are immune cells that capture and present antigens to T cells, activating an immune response. Researchers have discovered that short-chain fatty acids produced by intestinal bacteria regulate a crucial step in this process, the extension of dendritic 'arms.' This breakthrough finding could potentially lead to the development of disease prevention strategies involving beneficial bacteria and new drugs targeting the regulation of dendritic cell function.

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Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.

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Researchers have discovered a protein that seals plant roots to regulate the uptake of nutrients and water from the soil, the discovery could help develop climate proof crops that require less water and chemical fertilizers.   

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Researchers have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.

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Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems. For a long time, a certain type of fossil lipid, so-called 2-methylhopanes, was considered to be an important biomarker for Cyanobacteria in sediments, some of which are hundreds of millions of years old. However, this came into doubt when it turned out that not only Cyanobacteria but also Alphaproteobacteria are genetically capable of producing these lipids.

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Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell. A study suggests that mammalian cells internalize phages as a resource to promote cellular growth and survival.

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Special proteins -- known as membrane transporters -- are key to the mobility of sperm cells. A research team has, with the aid of cryo-electron microscopy, succeeded in decoding the structure of such a transporter and its mechanism. These findings will enable a better understanding of the molecular foundations of reproductive capacity and could, in the long term, contribute to developing new approaches to treating fertility disorders and new methods of specific contraception.

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A team of scientists has used multiple space and ground-based telescopes to observe an exceptionally bright gamma-ray burst, GRB 230307A, and identify the neutron star merger that generated an explosion that created the burst. Webb also helped scientists detect the chemical element tellurium in the explosion's aftermath.

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A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.

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Opening a clamshell of berries and seeing them coated in fuzzy mold is a downer. And it's no small problem. Gray mold and other fungi, which cause fruit to rot, lead to significant economic losses and food waste. Now, researchers report that compounds from sunflower crop waste prevented rotting in blueberries. They suggest the food industry could use these natural compounds to protect against post-harvest diseases.

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Eggs of the mosquito that carries Zika virus can tolerate extended desiccation by altering their metabolism, according to a new study. The finding offers potential new ways to control the spread of this mosquito.