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Categories: Biology: Genetics, Space: Cosmology

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The Bachman's warbler, a songbird that was last seen in North America nearly 40 years ago, was a distinct species and not a hybrid of its two living sister species, according a new study in which the full genomes of seven museum specimens of the bird were sequenced.

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Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.

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Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.

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Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.

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An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.

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The cosmos is a unique laboratory for testing the laws of physics, in particular those of Euler and Einstein. Euler described the movements of celestial objects, while Einstein described the way in which celestial objects distort the Universe. Since the discovery of dark matter and the acceleration of the Universe's expansion, the validity of their equations has been put to the test: are they capable of explaining these mysterious phenomena? A team has developed the first method to find out. It considers a never-before-used measure: time distortion.

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Astronomers studying a powerful gamma-ray burst, may have detected a never-before-seen way to destroy a star. Unlike most GRBs, which are caused by exploding massive stars or the chance mergers of neutron stars, astronomers have concluded that this GRB came instead from the collision of stars or stellar remnants in the jam-packed environment surrounding a supermassive black hole at the core of an ancient galaxy.

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For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.

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Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.

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DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.

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Researchers have discovered that extracts from plants used by the Kwakwaka'wakw First Nations peoples in their traditional botanical medicine practices are able to rescue the function of ion channel proteins carrying mutations that cause human Episodic Ataxia.

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Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.

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Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.

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A detailed, high-resolution map of the rusty patched bumble bee's genome has been released, offering new approaches for bringing the native pollinator back from the danger of extinction. Putting together the rusty patched bumble bee genome is part of the Beenome 100 project, a first-of-its-kind effort to create a library of high-quality, highly detailed genome maps of 100 or more diverse bee species found in the United States.

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In the face of the biodiversity crisis, and alarming data showing a 69% decline in global animal populations since 1970, researchers are banking on a cool solution to help save species from extinction. Much like egg-freezing is used to preserve human fertility options for a later date, the cryo-freezing of genetic samples taken from animals may play an essential role in curbing species extinctions. A new study sheds light on the immense potential of living cell banks, also known as cryobanks, to contribute to global conservation priorities.

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Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.

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Biologists provide evidence for an alternative genetic mechanism that can lead to plants becoming self-pollinators.

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Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.

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A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.

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Researchers reveal a theoretical breakthrough that may explain both the nature of invisible dark matter and the large-scale structure of the universe known as the cosmic web. The result establishes a new link between these two longstanding problems in astronomy, opening new possibilities for understanding the cosmos. The research suggests that the 'clumpiness problem,' which centres on the unexpectedly even distribution of matter on large scales throughout the cosmos, may be a sign that dark matter is composed of hypothetical, ultra-light particles called axions. The implications of proving the existence of hard-to-detect axions extend beyond understanding dark matter and could address fundamental questions about the nature of the universe itself.