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Categories: Biology: Genetics, Space: Cosmology
Published New class of antibiotics to fight resistant bacteria



Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.
Published Symbiotic and pathogenic fungi may use similar molecular tools to manipulate plants



Symbiotic and pathogenic fungi that interact with plants are distantly related and don't share many genetic similarities. Comparing plant pathogenic fungi and plant symbiotic fungi, scientists at the Sainsbury Laboratory Cambridge University (SLCU) have discovered that these remote relatives are using a similar group of proteins to manipulate and live within plants.
Published DNA damage repaired by antioxidant enzymes



In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.
Published Engineers report low-cost human biomarker sensor designs



Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.
Published Honey bee colony aggression linked to gene regulatory networks



In honey bees, the role a bee plays in the colony changes as they age. Younger bees perform duties inside the hive, such as nursing and wax building, while older bees transition to roles outside of the hive, either foraging for food (foragers) or defending the colony (soldiers). What determines whether older bees become foragers or soldiers is unknown, but a new studyexplores the genetic mechanisms underlying the collective behavior of colony defense, and how these mechanisms relate to the colony's overall aggression.
Published Astrophysicists confirm the faintest galaxy ever seen in the early universe



After the Big Bang, the universe expanded and cooled sufficiently for hydrogen atoms to form. In the absence of light from the first stars and galaxies, the universe entered a period known as the cosmic dark ages. The first stars and galaxies appeared several hundred million years later and began burning away the hydrogen fog left over from the Big Bang, rendering the universe transparent, like it is today. Researchers have now confirmed the existence of a distant, faint galaxy typical of those whose light burned through the hydrogen atoms; the finding should help them understand how the cosmic dark ages ended.
Published Researchers show mobile elements monkeying around the genome



Whole-genomic sequencing has revolutionized the amount and detail of genetic diversity now available to researchers to study. While the researchers previously had looked at a few hundred mobile elements or 'jumping genes,' primarily of the Alu and L1 types, they were now able to analyze over 200,000 elements computationally, confirming and expanding on previous studies. Their findings provide more evidence of the fluidity of species and continuous spread of mobile and transposable genetic elements.
Published A protein mines, sorts rare earths better than humans, paving way for green tech



Rare earth elements, like neodymium and dysprosium, are a critical component to almost all modern technologies, from smartphones to hard drives, but they are notoriously hard to separate from the Earth's crust and from one another. Scientists have discovered a new mechanism by which bacteria can select between different rare earth elements, using the ability of a bacterial protein to bind to another unit of itself, or 'dimerize,' when it is bound to certain rare earths, but prefer to remain a single unit, or 'monomer,' when bound to others.
Published Phenomenal phytoplankton: Scientists uncover cellular process behind oxygen production



According to new research, the amount of oxygen in one of 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton. The new study identifies how a proton pumping enzyme (known as VHA) aids in global oxygen production and carbon fixation from phytoplankton.
Published Geneticists discover hidden 'whole genome duplication' that may explain why some species survived mass extinctions



Geneticists have unearthed a major event in the ancient history of sturgeons and paddlefish that has significant implications for the way we understand evolution. They have pinpointed a previously hidden 'whole genome duplication' (WGD) in the common ancestor of these species, which seemingly opened the door to genetic variations that may have conferred an advantage around the time of a major mass extinction some 200 million years ago.
Published How the flu virus hacks our cells



Influenza epidemics, caused by influenza A or B viruses, result in acute respiratory infection. They kill half a million people worldwide every year. These viruses can also wreak havoc on animals, as in the case of avian flu. A team has now identified how the influenza A virus manages to penetrate cells to infect them. By attaching itself to a receptor on the cell surface, it hijacks the iron transport mechanism to start its infection cycle. By blocking the receptor involved, the researchers were also able to significantly reduce its ability to invade cells. These results highlight a vulnerability that could be exploited to combat the virus.
Published Plants can distinguish when touch starts and stops, study suggests



Even without nerves, plants can sense when something touches them and when it lets go, a study has found. In a set of experiments, individual plant cells responded to the touch of a very fine glass rod by sending slow waves of calcium signals to other plant cells, and when that pressure was released, they sent much more rapid waves. While scientists have known that plants can respond to touch, this study shows that plant cells send different signals when touch is initiated and ended.
Published Eat right, live longer: Could a moderate protein diet be the coveted elixir of youth?



Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers fed isocaloric diets with varying amounts of protein to young and middle-aged male mice. They found that the mice were metabolically healthier when fed moderate-protein diets. These findings could provide valuable insights into developing nutritional interventions and improving metabolic health in people.
Published Light conveyed by the signal transmitting molecule sucrose controls growth of plant roots



Researchers shows how information about the quantity of absorbed light passes from the leaves to the roots. Photosynthetic sucrose not only supplies roots with carbohydrates but also acts as a signal transmitter for light-dependent root architecture.
Published Scientists unveil RNA-guided mechanisms driving cell fate



The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published Evolution driving improvements in racehorse speed



A new study has found that genetic improvement is underlying the increasing speed of Britain's thoroughbreds. This contrasts with earlier studies that suggested racehorses were showing no genetic improvement in response to selection by breeders.
Published X-ray emissions from black hole jets vary unexpectedly, challenging leading model of particle acceleration



Black hole jets are known to emit x-rays, but how they accelerate particles to this high-energy state is still a mystery. Surprising new findings appear to rule out a leading theory, opening the door to reimagining how particle acceleration works. One model of how jets generate x-rays expects the jets' x-ray emissions to remain stable over long time scales. However, the new paper found that the x-ray emissions of a statistically significant number of jets varied over just a few years.
Published Groundbreaking images of root chemicals offer new insights on plant growth



Applying imaging technology to plant roots, researchers have developed a new understanding of chemicals that are responsible for plant growth. The chemical 'roadmap' identifies where key molecules are distributed along corn roots and how their placement factors into the plant's maturation.
Published Protein-based nano-'computer' evolves in ability to influence cell behavior



The first protein-based nano-computing agent that functions as a circuit has been created. The milestone puts them one step closer to developing next-generation cell-based therapies to treat diseases like diabetes and cancer.
Published How sweet it is: The fruit fly gut influences reproduction by 'tasting' fructose



A research group has found that in fruit flies (Drosophila melanogaster), circulating fructose derived from dietary sugar is needed for enhanced egg production after mating. In this species, circulating fructose is required for an increase in germline stem cells, which divide into reproductive cells. This increase leads to enhanced post-mating egg production. These findings may help to determine whether fructose influences the reproduction of mammals, including humans.