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Categories: Biology: Genetics, Space: Cosmology
Published Researchers successfully induce primate oocytes in the lab
(via sciencedaily.com) Original source The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published Helium nuclei research advances our understanding of cosmic ray origin and propagation
(via sciencedaily.com) Original source The latest observations from Low Earth Orbit with the International Space Station provide further evidence of spectral hardening and softening of cosmic ray particles.
Published How tasty is the food?
(via sciencedaily.com) Original source A hormone and specialized brain cells regulate feeding behavior in mice.
Published Where do our limbs come from?
(via sciencedaily.com) Original source Scientists have uncovered new clues about the origin of paired appendages -- a major evolutionary step that remains unresolved and highly debated.
Published A look into the heart of cellular waste disposal
(via sciencedaily.com) Original source Researchers reveal how a nanomachine takes care of cleaning up inside the cell.
Published Engineers create bacteria that can synthesize an unnatural amino acid
(via sciencedaily.com) Original source Researchers have engineered bacteria to synthesize an amino acid that contains a rare functional group that others have shown to have implications in the regulation of our immune system. The researchers also taught a single bacterial strain to create the amino acid and place it at specific sites within target proteins. These findings provide a foundation for developing unique vaccines and immunotherapies in the future.
Published Researchers find new mechanism for sodium salt detoxification in plants
(via sciencedaily.com) Original source A team of researchers has found a mechanism in thale cress (Arabidopsis thaliana) which enables plants to provide protection against salt stress for their sensitive stem cells in the meristem at the root tip.
Published Study may explain why high-sugar diets can worsen IBD
(via sciencedaily.com) Original source Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study that could help get to the bottom of why limiting sugary foods can ease symptoms for patients with IBD.
Published A multiomics approach provides insights into flu severity
(via sciencedaily.com) Original source Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.
Published Designing synthetic receptors for precise cell control
(via sciencedaily.com) Original source Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications.
Published Under control to the very end -- how our cells kill themselves
(via sciencedaily.com) Original source Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers have now been able to elucidate the exact mechanism at the atomic level.
Published A guide through the genome
(via sciencedaily.com) Original source Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests. One of the greatest challenges in modern plant research is to identify the differences in genetic information that are responsible for this variation.
Published How plants use sugar to produce roots
(via sciencedaily.com) Original source Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.
Published An X-ray look at the heart of powerful quasars
(via sciencedaily.com) Original source Researchers have observed the X-ray emission of the most luminous quasar seen in the last 9 billion years of cosmic history, known as SMSS J114447.77-430859.3, or J1144 for short. The new perspective sheds light on the inner workings of quasars and how they interact with their environment.
Published Synthetic biology: proteins set vesicles in motion
(via sciencedaily.com) Original source Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.
Published Cancer cells use a new fuel in absence of sugar
(via sciencedaily.com) Original source Researchers have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings show that cancer cells can adapt when they don't have access to glucose.
Published Watch these cells rapidly create protrusions for exploration and movement
(via sciencedaily.com) Original source In order to move, cells must be able to rapidly change shape. A team of researchers show that cells achieve this by storing extra 'skin' in folds and bumps on their surface. This cell surface excess can be rapidly deployed to cover temporary protrusions and then folded away for next time.
Published Scales or feathers? It all comes down to a few genes
(via sciencedaily.com) Original source Scales, spines, feathers and hair are examples of vertebrate skin appendages, which constitute a remarkably diverse group of micro-organs. Despite their natural multitude of forms, these appendages share early developmental processes at the embryonic stage. Researchers have discovered how to permanently transform the scales that normally cover the feet of chickens into feathers, by specifically modifying the expression of certain genes.
Published What did the earliest animals look like?
(via sciencedaily.com) Original source Surprisingly, genome comparisons have failed to resolve a major question in animal evolution: Which living animals are the descendants of the earliest animals to evolve in the world's oceans? Scientists performed a detailed chromosomal analysis that comes down definitively in favor of comb jellies, or ctenophores, as the most recent common ancestor of all animals, or the sister taxa to all animals. Sponges evolved later.
Published Radio signal reveals supernova origin
(via sciencedaily.com) Original source Astronomers reveal the origin of a thermonuclear supernova explosion. Strong emission lines of helium and the first detection of such a supernova in radio waves show that the exploding white dwarf star had a helium-rich companion.