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Categories: Biology: Genetics, Ecology: Endangered Species
Published Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time



Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
Published Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease



By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.
Published Silkworms help grow better organ-like tissues in labs



Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.
Published Scientists 'read' the messages in chemical clues left by coral reef inhabitants



What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex 'soup' that is hard for scientists to decipher. Now, researchers have demonstrated a way to extract and identify these indicator compounds in seawater. They found metabolites previously undetected on reefs, including three that may represent different reef organisms.
Published Better farming through nanotechnology



Advanced technologies enable the controlled release of medicine to specific cells in the body. Scientists argue these same technologies must be applied to agriculture if growers are to meet increasing global food demands.
Published Determining sex in ants



Researchers have been investigating the molecular mechanisms responsible for determining sex in ants. Although the vast majority of an ant colony consists of female workers, males are essential to the continuing survival of the species. In order to uncover the mechanisms involved, the researchers decided to focus on diploid males, which occasionally occur in the Argentine ant.
Published Novel lipopeptide proves lethal against Staphylococcus areus



Researchers provide the first insight into the mode of action of the lipopeptide serrawettin W2-FL10, derived from Serratia marcescens. This lipopeptide targets the cell membrane of S. aureus, causing lesions which result in the leakage of intracellular components and ultimately cell death.
Published Marsupials key to discovering the origin of heater organs in mammals



Around 100 million years ago, a remarkable evolutionary shift allowed placental mammals to diversify and conquer many cold regions of our planet. New research shows that the typical mammalian heater organ, brown fat, evolved exclusively in modern placental mammals. The research team demonstrated that marsupials, our distant relatives, possess a not fully evolved form of brown fat. They discovered that the pivotal heat-producing protein called UCP1 became active after the divergence of placental and marsupial mammals. This finding is crucial for understanding the role of brown fat in mammalian evolution, endothermy, and metabolism.
Published New technique reveals how gene transcription is coordinated in cells



Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.
Published Father's diet before conception influences children's health



A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.
Published Exercising during pregnancy normalizes eating behaviors in offspring from obese mice



Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.
Published Human activity contributed to woolly rhinoceros' extinction



Researchers have discovered sustained hunting by humans prevented the woolly rhinoceros from accessing favourable habitats as Earth warmed following the Last Ice Age.
Published Frequent mowing puts poisonous weed into survival mode



A study has found that frequent mowing of Solanum elaeagnifolium, also known as silverleaf nightshade, may help create a 'superweed.' A professor of entomology and plant pathology has been studying silverleaf nightshade for more than a decade. New findings have shown that the more silverleaf nightshade was mowed, the more it developed ways to avoid destruction. The taproot went down further, nearly 5 feet deep, in the first generation of mowed plants. More spikes popped out on the stem as a defense against caterpillars feeding on the flowers. The flowers became more toxic to caterpillars, leading to less pressure from natural predators.
Published Key nutrients help plants beat the heat



Scientists have discovered some of the molecular mechanisms controlling how plants -- including important crops like soybean and rice -- will respond to rising global temperatures, finding higher temperatures make root systems grow faster, but sustaining this increased growth speed depends on high levels of nitrogen and phosphorus in the soil. The discoveries point to the necessity of nitrogen and phosphorus-rich soil to promote crop growth and create nutritious crops, in addition to aiding a mission to create more resilient crops in the face of climate change.
Published Urgent need for action now for increasing threat from invasive alien species



Urgent action now is needed to tackle the major and growing global issue of invasive alien species, says a team of 88 experts from 47 countries. The paper follows the (IPBES) thematic assessment report on invasive alien species and their control. The experts say co-developing management actions with multiple stakeholders including government and private sector stakeholders, and Indigenous Peoples and local communities will be critical to achieving success in addressing biological invasions.
Published Paving the way for hydrogen from algae enzymes



Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.
Published Researchers discover 'trojan horse' virus hiding in human parasite



An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.
Published The world's most powerful anti-fungal chemistries cause fungal pathogens to self-destruct



Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
Published New, modified CRISPR protein can fit inside virus used for gene therapy



Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published Tracing the evolution of ferns' surprisingly sweet defense strategy



Plants and the animals that eat them have evolved together in fascinating ways, creating a dynamic interplay of survival strategies. Many plants have developed physical and chemical defenses to fend off herbivores. A well-known strategy in flowering plants is to produce nectar to attract 'ant bodyguards.' Recent research explores the evolution of this same defense strategy in ferns.